| 9/2/2022 | Albright (0-10) | 0 | at | Salisbury | 49 | MidAC | ||
| 9/10/2022 | Salisbury | 21 | at | Stevenson (8-3) | 35 | at MidAC | ||
| 9/17/2022 | Ave Maria (5-3) | 14 | at | Salisbury | 42 | Sun (NAIA) | ||
| 9/24/2022 | Salisbury | 35 | at | Western New England (4-6) | 0 | at CCF | ||
| 10/1/2022 | Montclair State (2-8,0-6) | 7 | at | Salisbury | 30 | |||
| 10/8/2022 | Salisbury | 23 | at | William Paterson (5-5,2-4) | 0 | |||
| 10/22/2022 | Salisbury | 70 | at | New Jersey (3-6,2-4) | 17 | |||
| 10/29/2022 | Rowan (7-3,4-2) | 23 | at | Salisbury | 28 | |||
| 11/5/2022 | Salisbury | 32 | at | Kean (3-7,2-4) | 17 | |||
| 11/12/2022 | Christopher Newport (7-3,5-1) | 33 | at | Salisbury | 36 | |||
| 11/19/2022 | Salisbury | 0 | at | Mount Union (14-1) | 51 | D3 Championship Round 1 | at OAC |
| vs Salisbury | vs Other Opponents | Salisbury compared to OOs | |
| Record: | 2-9 | 56-46 | |
| Points Scored: | 17.91 | 24.27 | 6.36 |
| Points Allowed: | 33.27 | 18.26 | 15.01 |
| Margin: | -15.36 | 6.01 | 21.37 |
| Total Points: | 51.18 | 42.53 | 8.65 |