| 9/3/2022 | Tiffin | 42 | at | Walsh (1-9,1-7) | 0 | |||
| 9/10/2022 | Ohio Dominican (7-3,6-2) | 13 | at | Tiffin | 28 | |||
| 9/17/2022 | Indianapolis (9-2) | 27 | at | Tiffin | 20 | GLV | ||
| 9/24/2022 | Tiffin | 17 | at | Truman State (9-2) | 18 | OT | at GLV | |
| 10/1/2022 | Lake Erie (3-8,3-5) | 27 | at | Tiffin | 52 | |||
| 10/8/2022 | Tiffin | 41 | at | Hillsdale (5-6,4-4) | 0 | |||
| 10/22/2022 | Tiffin | 20 | at | Ashland (10-2,7-1) | 28 | |||
| 10/29/2022 | Northwood (3-8,2-6) | 3 | at | Tiffin | 48 | |||
| 11/5/2022 | Tiffin | 72 | at | Kentucky Wesleyan (2-9,1-7) | 13 | |||
| 11/12/2022 | Findlay (7-4,6-2) | 27 | at | Tiffin | 25 | |||
| 12/3/2022 | Tiffin | 27 | vs | Truman State (9-2) | 28 | Hobart IN | vs GLV |
| vs Tiffin | vs Other Opponents | Tiffin compared to OOs | |
| Record: | 5-6 | 58-49 | |
| Points Scored: | 16.73 | 26.60 | 9.87 |
| Points Allowed: | 35.64 | 24.08 | 11.56 |
| Margin: | -18.91 | 2.52 | 21.43 |
| Total Points: | 52.37 | 50.68 | 1.69 |