| 9/1/2022 | Notre Dame OH (9-3) | 14 | at | Ashland | 31 | MtnE | ||
| 9/10/2022 | Ashland | 28 | at | Findlay (7-4,6-2) | 3 | |||
| 9/24/2022 | Ashland | 34 | at | Quincy (4-7) | 14 | at GLV | ||
| 10/1/2022 | Northwood (3-8,2-6) | 17 | at | Ashland | 56 | |||
| 10/8/2022 | Ashland | 35 | at | Walsh (1-9,1-7) | 0 | |||
| 10/15/2022 | Ohio Dominican (7-3,6-2) | 7 | at | Ashland | 14 | |||
| 10/22/2022 | Tiffin (6-5,6-2) | 20 | at | Ashland | 28 | |||
| 10/29/2022 | Ashland | 20 | at | Hillsdale (5-6,4-4) | 36 | |||
| 11/5/2022 | Ashland | 31 | at | Lake Erie (3-8,3-5) | 23 | |||
| 11/12/2022 | Kentucky Wesleyan (2-9,1-7) | 10 | at | Ashland | 41 | |||
| 11/19/2022 | Notre Dame OH (9-3) | 13 | at | Ashland | 20 | D2 Championship Round 1 | MtnE | |
| 11/26/2022 | Ashland | 13 | at | Indiana PA (10-2) | 19 | D2 Playoffs Round 2 | at PSAC |
| vs Ashland | vs Other Opponents | Ashland compared to OOs | |
| Record: | 2-10 | 64-55 | |
| Points Scored: | 14.67 | 27.71 | 13.04 |
| Points Allowed: | 29.25 | 24.78 | 4.47 |
| Margin: | -14.58 | 2.93 | 17.51 |
| Total Points: | 43.92 | 52.49 | -8.57 |