| 9/1/2022 | Lincoln CA (2-9) | 7 | at | Texas A&M-Commerce | 52 | None (Unk?) | ||
| 9/10/2022 | Texas A&M-Commerce | 25 | at | Tennessee Tech (4-7) | 26 | at OVC | ||
| 9/17/2022 | Texas A&M-Commerce | 17 | at | Sam Houston (5-4) | 27 | at WAC | ||
| 9/24/2022 | North American U (1-8) | 3 | at | Texas A&M-Commerce | 63 | None (Unk?) | ||
| 10/8/2022 | Texas A&M-Commerce | 31 | at | Southeastern Louisiana (9-4,5-1) | 28 | |||
| 10/15/2022 | Texas A&M-Commerce | 40 | at | McNeese State (4-7,2-4) | 15 | |||
| 10/22/2022 | Houston Christian (2-9,1-5) | 3 | at | Texas A&M-Commerce | 31 | |||
| 10/29/2022 | Incarnate Word (12-2,6-1) | 35 | at | Texas A&M-Commerce | 7 | |||
| 11/5/2022 | Northwestern State (4-7,4-2) | 41 | at | Texas A&M-Commerce | 14 | |||
| 11/12/2022 | Texas A&M-Commerce | 10 | at | Nicholls State (3-8,3-4) | 12 | |||
| 11/19/2022 | Tennessee State (4-7) | 22 | at | Texas A&M-Commerce | 14 | OVC |
| vs Texas A&M-Commerce | vs Other Opponents | Texas A&M-Commerce compared to OOs | |
| Record: | 6-5 | 44-67 | |
| Points Scored: | 19.91 | 24.58 | 4.67 |
| Points Allowed: | 27.64 | 33.03 | -5.39 |
| Margin: | -7.73 | -8.45 | -0.72 |
| Total Points: | 47.55 | 57.61 | -10.06 |