| 8/27/2022 | North American U | 13 | at | Southeastern FL (6-4) | 54 | at Sun | ||
| 9/3/2022 | North American U | 0 | at | Texas A&M-Kingsville (7-5) | 60 | at LSC | ||
| 9/10/2022 | North American U | 3 | at | Ark Pine Bluff (3-8) | 76 | at SWAC | ||
| 9/17/2022 | North American U | 0 | at | St Thomas FL (8-2) | 52 | at Sun | ||
| 9/24/2022 | North American U | 3 | at | Texas A&M-Commerce (5-6) | 63 | at SLC | ||
| 10/1/2022 | Texas Lutheran (4-6) | 45 | at | North American U | 17 | ASWC (D3) | ||
| 10/22/2022 | Arkansas Baptist (1-7,0-1) | 14 | at | North American U | 47 | |||
| 11/5/2022 | North American U | 7 | at | Texas Wesleyan (8-2) | 61 | at Soon | ||
| 11/12/2022 | North American U | 6 | at | East Texas Baptist (5-5) | 43 | at ASWC |
| vs North American U | vs Other Opponents | North American U compared to OOs | |
| Record: | 8-1 | 39-44 | |
| Points Scored: | 52.00 | 25.63 | -26.37 |
| Points Allowed: | 10.67 | 26.90 | -16.23 |
| Margin: | 41.33 | -1.27 | -42.60 |
| Total Points: | 62.67 | 52.53 | 10.14 |