| 9/10/2022 | Lindenwood | 21 | at | Houston Christian (2-9) | 20 | at SLC | ||
| 9/17/2022 | Keiser (10-4) | 3 | at | Lindenwood | 37 | Sun (NAIA) | ||
| 9/24/2022 | Lindenwood | 26 | at | Tennessee-Martin (7-4,5-0) | 56 | |||
| 10/1/2022 | SE Missouri State (9-3,5-0) | 49 | at | Lindenwood | 28 | |||
| 10/8/2022 | Lindenwood | 52 | at | Central Arkansas (5-6) | 49 | at ASUN | ||
| 10/15/2022 | Lindenwood | 37 | at | Eastern Illinois (2-9,1-5) | 34 | OT | ||
| 10/22/2022 | Murray State (2-9,1-4) | 18 | at | Lindenwood | 33 | |||
| 10/29/2022 | William Jewell (2-9) | 23 | at | Lindenwood | 64 | GLV (D2) | ||
| 11/5/2022 | Lindenwood | 34 | at | Tennessee Tech (4-7,2-3) | 35 | |||
| 11/12/2022 | McKendree (5-6) | 35 | at | Lindenwood | 63 | GLV (D2) |
| vs Lindenwood | vs Other Opponents | Lindenwood compared to OOs | |
| Record: | 3-7 | 45-59 | |
| Points Scored: | 32.20 | 26.52 | -5.68 |
| Points Allowed: | 39.50 | 31.19 | 8.31 |
| Margin: | -7.30 | -4.67 | 2.63 |
| Total Points: | 71.70 | 57.71 | 13.99 |