| 9/2/2022 | Tennessee Tech (4-7) | 10 | at | Kansas | 56 | OVC (1AA) | ||
| 9/10/2022 | Kansas | 55 | at | West Virginia (5-7,3-6) | 42 | OT | ||
| 9/17/2022 | Kansas | 48 | at | Houston (8-5) | 30 | at AAC | ||
| 9/24/2022 | Duke (9-4) | 27 | at | Kansas | 35 | ACC | ||
| 10/1/2022 | Iowa State (4-8,1-8) | 11 | at | Kansas | 14 | |||
| 10/8/2022 | TCU (13-2,9-1) | 38 | at | Kansas | 31 | |||
| 10/15/2022 | Kansas | 42 | at | Oklahoma (6-7,3-6) | 52 | |||
| 10/22/2022 | Kansas | 23 | at | Baylor (6-7,4-5) | 35 | |||
| 11/5/2022 | Oklahoma State (7-6,4-5) | 16 | at | Kansas | 37 | |||
| 11/12/2022 | Kansas | 28 | at | Texas Tech (8-5,5-4) | 43 | |||
| 11/19/2022 | Texas (8-5,6-3) | 55 | at | Kansas | 14 | |||
| 11/26/2022 | Kansas | 27 | at | Kansas State (10-4,8-2) | 47 | |||
| 12/28/2022 | Kansas | 53 | vs | Arkansas (7-6) | 55 | 3OT | Memphis TN | vs SEC |
| vs Kansas | vs Other Opponents | Kansas compared to OOs | |
| Record: | 7-6 | 88-67 | |
| Points Scored: | 35.46 | 31.63 | -3.83 |
| Points Allowed: | 35.62 | 26.77 | 8.85 |
| Margin: | -0.16 | 4.86 | 5.02 |
| Total Points: | 71.08 | 58.40 | 12.68 |