| 9/1/2022 | West Virginia | 31 | at | Pittsburgh (9-4) | 38 | at ACC | ||
| 9/10/2022 | Kansas (6-7,3-6) | 55 | at | West Virginia | 42 | OT | ||
| 9/17/2022 | Towson (6-5) | 7 | at | West Virginia | 65 | CAAF (1AA) | ||
| 9/22/2022 | West Virginia | 33 | at | Virginia Tech (3-8) | 10 | at ACC | ||
| 10/1/2022 | West Virginia | 20 | at | Texas (8-5,6-3) | 38 | |||
| 10/13/2022 | Baylor (6-7,4-5) | 40 | at | West Virginia | 43 | |||
| 10/22/2022 | West Virginia | 10 | at | Texas Tech (8-5,5-4) | 48 | |||
| 10/29/2022 | TCU (13-2,9-1) | 41 | at | West Virginia | 31 | |||
| 11/5/2022 | West Virginia | 14 | at | Iowa State (4-8,1-8) | 31 | |||
| 11/12/2022 | Oklahoma (6-7,3-6) | 20 | at | West Virginia | 23 | |||
| 11/19/2022 | Kansas State (10-4,8-2) | 48 | at | West Virginia | 31 | |||
| 11/26/2022 | West Virginia | 24 | at | Oklahoma State (7-6,4-5) | 19 |
| vs West Virginia | vs Other Opponents | West Virginia compared to OOs | |
| Record: | 7-5 | 79-63 | |
| Points Scored: | 32.92 | 30.52 | -2.40 |
| Points Allowed: | 30.58 | 26.39 | 4.19 |
| Margin: | 2.34 | 4.13 | 1.79 |
| Total Points: | 63.50 | 56.91 | 6.59 |