| 9/4/2021 | Bloomsburg | 13 | at | Stonehill (8-2) | 35 | at NE10 | ||
| 9/11/2021 | Bloomsburg | 7 | at | Seton Hill (5-6,4-6) | 13 | |||
| 9/18/2021 | Gannon (5-6,4-6) | 27 | at | Bloomsburg | 31 | |||
| 9/25/2021 | Bloomsburg | 7 | at | Shippensburg (9-2,8-2) | 51 | |||
| 10/2/2021 | Bloomsburg | 20 | at | West Chester (6-5,6-4) | 21 | |||
| 10/9/2021 | Kutztown (11-2,9-2) | 34 | at | Bloomsburg | 7 | |||
| 10/16/2021 | Lock Haven (1-10,0-10) | 0 | at | Bloomsburg | 44 | |||
| 10/23/2021 | Bloomsburg | 14 | at | East Stroudsburg (5-6,4-6) | 35 | |||
| 10/30/2021 | Shepherd (13-2,10-1) | 62 | at | Bloomsburg | 18 | |||
| 11/6/2021 | Bloomsburg | 38 | at | Millersville (2-9,2-8) | 35 | |||
| 11/13/2021 | California PA (9-1,8-1) | 24 | at | Bloomsburg | 9 |
| vs Bloomsburg | vs Other Opponents | Bloomsburg compared to OOs | |
| Record: | 8-3 | 66-48 | |
| Points Scored: | 30.64 | 26.52 | -4.12 |
| Points Allowed: | 18.91 | 24.45 | -5.54 |
| Margin: | 11.73 | 2.07 | -9.66 |
| Total Points: | 49.55 | 50.97 | -1.42 |