| 9/4/2021 | Valparaiso | 10 | at | Indiana Wesleyan (7-1) | 28 | at MSFA | ||
| 9/11/2021 | Valparaiso | 0 | at | North Dakota State (14-1) | 64 | at MVC | ||
| 9/18/2021 | Dartmouth (9-1) | 28 | at | Valparaiso | 18 | Ivy | ||
| 9/25/2021 | Valparaiso | 24 | at | Drake (2-8,1-6) | 21 | |||
| 10/2/2021 | Marist (5-5,5-3) | 27 | at | Valparaiso | 24 | OT | ||
| 10/9/2021 | Valparaiso | 13 | at | St Thomas (7-3,6-2) | 20 | |||
| 10/23/2021 | Dayton (6-4,5-3) | 28 | at | Valparaiso | 45 | |||
| 10/30/2021 | Valparaiso | 14 | at | San Diego (7-4,7-1) | 21 | |||
| 11/6/2021 | Presbyterian (2-9,0-8) | 55 | at | Valparaiso | 65 | |||
| 11/13/2021 | Valparaiso | 47 | at | Butler (3-8,1-7) | 3 | |||
| 11/20/2021 | Morehead State (7-4,6-2) | 51 | at | Valparaiso | 38 |
| vs Valparaiso | vs Other Opponents | Valparaiso compared to OOs | |
| Record: | 7-4 | 62-44 | |
| Points Scored: | 31.45 | 28.15 | -3.30 |
| Points Allowed: | 27.09 | 24.97 | 2.12 |
| Margin: | 4.36 | 3.18 | -1.18 |
| Total Points: | 58.54 | 53.12 | 5.42 |