| 9/18/2021 | Dartmouth | 28 | at | Valparaiso (4-7) | 18 | at Pio | ||
| 9/25/2021 | Sacred Heart (8-4) | 3 | at | Dartmouth | 41 | NE | ||
| 10/1/2021 | Dartmouth | 31 | at | Pennsylvania (3-7,1-6) | 7 | |||
| 10/9/2021 | Yale (5-5,4-3) | 17 | at | Dartmouth | 24 | OT | ||
| 10/16/2021 | Dartmouth | 38 | at | New Hampshire (3-8) | 21 | at CAAF | ||
| 10/22/2021 | Columbia (7-3,4-3) | 19 | at | Dartmouth | 0 | |||
| 10/30/2021 | Dartmouth | 20 | at | Harvard (8-2,5-2) | 17 | |||
| 11/5/2021 | Princeton (9-1,6-1) | 7 | at | Dartmouth | 31 | |||
| 11/13/2021 | Cornell (2-8,1-6) | 7 | at | Dartmouth | 41 | |||
| 11/20/2021 | Dartmouth | 52 | at | Brown (2-8,1-6) | 31 |
| vs Dartmouth | vs Other Opponents | Dartmouth compared to OOs | |
| Record: | 1-9 | 50-44 | |
| Points Scored: | 14.70 | 26.20 | 11.50 |
| Points Allowed: | 30.60 | 24.00 | 6.60 |
| Margin: | -15.90 | 2.20 | 18.10 |
| Total Points: | 45.30 | 50.20 | -4.90 |