| 9/3/2016 | Rhode Island (2-9) | 6 | at | Kansas | 55 | CAAF (1AA) | ||
| 9/10/2016 | Ohio (8-6) | 37 | at | Kansas | 21 | MAC | ||
| 9/17/2016 | Kansas | 7 | at | Memphis (8-5) | 43 | at AAC | ||
| 9/29/2016 | Kansas | 19 | at | Texas Tech (5-7,3-6) | 55 | |||
| 10/8/2016 | TCU (6-7,4-5) | 24 | at | Kansas | 23 | |||
| 10/15/2016 | Kansas | 7 | at | Baylor (7-6,3-6) | 49 | |||
| 10/22/2016 | Oklahoma State (10-3,7-2) | 44 | at | Kansas | 20 | |||
| 10/29/2016 | Kansas | 3 | at | Oklahoma (11-2,9-0) | 56 | |||
| 11/5/2016 | Kansas | 21 | at | West Virginia (10-3,7-2) | 48 | |||
| 11/12/2016 | Iowa State (3-9,2-7) | 31 | at | Kansas | 24 | |||
| 11/19/2016 | Texas (5-7,3-6) | 21 | at | Kansas | 24 | OT | ||
| 11/26/2016 | Kansas | 19 | at | Kansas State (9-4,6-3) | 34 |
| vs Kansas | vs Other Opponents | Kansas compared to OOs | |
| Record: | 10-2 | 74-66 | |
| Points Scored: | 37.33 | 32.85 | -4.48 |
| Points Allowed: | 20.25 | 29.91 | -9.66 |
| Margin: | 17.08 | 2.94 | -14.14 |
| Total Points: | 57.58 | 62.76 | -5.18 |