| 9/3/2016 | Florida A&M (4-7) | 3 | at | Miami-Florida | 70 | MEAC (1AA) | ||
| 9/10/2016 | Florida Atlantic (3-9) | 10 | at | Miami-Florida | 38 | CUSA | ||
| 9/17/2016 | Miami-Florida | 45 | at | Appalachian State (10-3) | 10 | at SBC | ||
| 10/1/2016 | Miami-Florida | 35 | at | Georgia Tech (9-4,4-4) | 21 | |||
| 10/8/2016 | Florida State (10-3,5-3) | 20 | at | Miami-Florida | 19 | |||
| 10/15/2016 | North Carolina (8-5,5-3) | 20 | at | Miami-Florida | 13 | |||
| 10/20/2016 | Miami-Florida | 16 | at | Virginia Tech (10-4,6-3) | 37 | |||
| 10/29/2016 | Miami-Florida | 27 | at | Notre Dame (4-8) | 30 | at ND | ||
| 11/5/2016 | Pittsburgh (8-5,5-3) | 28 | at | Miami-Florida | 51 | |||
| 11/12/2016 | Miami-Florida | 34 | at | Virginia (2-10,1-7) | 14 | |||
| 11/19/2016 | Miami-Florida | 27 | at | North Carolina State (7-6,3-5) | 13 | |||
| 11/26/2016 | Duke (4-8,1-7) | 21 | at | Miami-Florida | 40 | |||
| 12/28/2016 | West Virginia (10-3) | 14 | vs | Miami-Florida | 31 | Russell Athletic Bowl (Orlando FL) | B12 |
| vs Miami-Florida | vs Other Opponents | Miami-Florida compared to OOs | |
| Record: | 4-9 | 85-66 | |
| Points Scored: | 18.54 | 30.49 | 11.95 |
| Points Allowed: | 34.31 | 26.84 | 7.47 |
| Margin: | -15.77 | 3.65 | 19.42 |
| Total Points: | 52.85 | 57.33 | -4.48 |