| 11-3 | — | 0 | (1 Common Ops) | 0 | Akron | 1-11 |
| W 24-10 at | 9/18/2010 | Buffalo (2-8) | 11/26/2010 | W 22-14 |
|
| 11-3 | — | 0 | (1 Common Ops) | 0 | Arkansas | 10-3 |
| W 10-6 vs | 12/31/2010 | Georgia (6-5) | 9/18/2010 | W 31-24 at |
|
| 11-3 | — | 0 | (2 Common Ops) | 0 | Army | 7-6 |
| W 61-14 at | 11/20/2010 | Tulane (4-6) | 10/9/2010 | W 41-23 at |
| W 17-7 | 12/4/2010 | SMU (7-5) | 12/30/2010 | W 16-14 vs |
| 2-0 | 11-11 | 2-0 |
|
| 11-3 | — | 0 | (1 Common Ops) | 0 | Auburn | 14-0 |
| W 10-6 vs | 12/31/2010 | Georgia (6-5) | 11/13/2010 | W 49-31 |
|
| 11-3 | — | 0 | (1 Common Ops) | 0 | Ball State | 4-8 |
| W 24-10 at | 9/18/2010 | Buffalo (2-8) | 11/12/2010 | W 20-3 at |
|
| 11-3 | — | 0 | (3 Common Ops) | 0 | Baylor | 7-6 |
| W 24-10 at | 9/18/2010 | Buffalo (2-8) | 9/11/2010 | W 34-6 |
| W 41-14 | 10/23/2010 | Rice (4-6) | 9/25/2010 | W 30-13 at |
| L 13-17 at | 9/25/2010 | Kansas State (6-5) | 10/23/2010 | W 47-42 |
| 2-1 | 12-19 | 3-0 |
|
| 11-3 | — | 0 | (1 Common Ops) | 0 | Boston College | 7-6 |
| L 21-28 | 9/11/2010 | North Carolina State (7-4) | 10/9/2010 | L 17-44 at |
|
| 11-3 | — | 0 | (2 Common Ops) | 0 | Bowling Green | 2-10 |
| W 24-10 at | 9/18/2010 | Buffalo (1-9) | 10/2/2010 | L 26-28 |
| W 35-14 at | 10/13/2010 | Marshall (5-5) | 9/18/2010 | W 44-28 |
| 2-0 | 6-14 | 1-1 |
|
| 11-3 | — | 0 | (1 Common Ops) | 0 | Cincinnati | 4-8 |
| L 21-28 | 9/11/2010 | North Carolina State (7-4) | 9/16/2010 | L 19-30 at |
|
| 11-3 | — | 0 | (1 Common Ops) | 0 | Clemson | 6-7 |
| L 21-28 | 9/11/2010 | North Carolina State (8-3) | 11/6/2010 | W 14-13 |
|
| 11-3 | — | 0 | (2 Common Ops) | 0 | Colorado | 5-7 |
| L 13-17 at | 9/25/2010 | Kansas State (6-5) | 11/20/2010 | W 44-36 |
| W 10-6 vs | 12/31/2010 | Georgia (6-5) | 10/2/2010 | W 29-27 |
| 1-1 | 12-10 | 2-0 |
|
| 11-3 | — | 0 | (1 Common Ops) | 0 | Connecticut | 8-5 |
| W 24-10 at | 9/18/2010 | Buffalo (2-8) | 9/25/2010 | W 45-21 |
|
| 10-3 | — | 1 | (7 Common Ops) | 0 | East Carolina | 6-6 |
| L 21-28 | 9/11/2010 | North Carolina State (8-3) | 10/16/2010 | W 33-27 1 |
| W 42-7 | 10/6/2010 | UAB (4-6) | 11/11/2010 | W 54-42 at |
| W 35-14 at | 10/13/2010 | Marshall (5-5) | 10/23/2010 | W 37-10 |
| W 41-14 | 10/23/2010 | Rice (3-7) | 11/20/2010 | L 38-62 at |
| L 21-31 | 11/13/2010 | Southern Miss (7-4) | 10/9/2010 | W 44-43 at |
| W 37-17 at | 11/27/2010 | Memphis (1-9) | 9/11/2010 | W 49-27 |
| W 17-7 | 12/4/2010 | SMU (6-6) | 11/26/2010 | L 38-45 1 |
| 5-2 | 34-40 | 5-2 |
|
| 11-3 | — | 0 | (1 Common Ops) | 0 | Eastern Michigan | 2-10 |
| W 24-10 at | 9/18/2010 | Buffalo (2-8) | 11/20/2010 | W 21-17 at |
|
| 11-3 | — | 0 | (1 Common Ops) | 0 | Florida | 8-5 |
| W 10-6 vs | 12/31/2010 | Georgia (6-5) | 10/30/2010 | W 34-31 1 vs |
|
| 11-3 | — | 0 | (1 Common Ops) | 0 | Florida Atlantic | 4-8 |
| W 42-7 | 10/6/2010 | UAB (4-6) | 9/2/2010 | W 32-31 at |
|
| 11-3 | — | 0 | (1 Common Ops) | 0 | Florida State | 10-4 |
| L 21-28 | 9/11/2010 | North Carolina State (7-4) | 10/28/2010 | L 24-28 at |
|
| 11-3 | — | 0 | (2 Common Ops) | 0 | Georgia Tech | 6-7 |
| L 21-28 | 9/11/2010 | North Carolina State (7-4) | 9/25/2010 | L 28-45 |
| W 10-6 vs | 12/31/2010 | Georgia (5-6) | 11/27/2010 | L 34-42 at |
| 1-1 | 12-10 | 0-2 |
|
| 10-3 | — | 1 | (5 Common Ops) | 0 | Houston | 5-6 |
| W 41-14 | 10/23/2010 | Rice (3-7) | 10/16/2010 | L 31-34 at |
| L 21-31 | 11/13/2010 | Southern Miss (6-5) | 11/20/2010 | L 41-59 at |
| W 61-14 at | 11/20/2010 | Tulane (4-6) | 9/25/2010 | W 42-23 |
| W 37-17 at | 11/27/2010 | Memphis (1-9) | 10/30/2010 | W 56-17 at |
| W 17-7 | 12/4/2010 | SMU (7-5) | 10/23/2010 | W 45-20 at |
| 4-1 | 21-32 | 3-2 |
|
| 11-3 | — | 0 | (1 Common Ops) | 0 | Idaho State | 0-2 |
| W 10-6 vs | 12/31/2010 | Georgia (5-6) | 11/6/2010 | L 7-55 at |
|
| 11-3 | — | 0 | (1 Common Ops) | 0 | Iowa State | 5-7 |
| L 13-17 at | 9/25/2010 | Kansas State (5-6) | 9/18/2010 | L 20-27 vs |
|
| 11-3 | — | 0 | (2 Common Ops) | 0 | Kansas | 3-9 |
| L 13-17 at | 9/25/2010 | Kansas State (5-6) | 10/14/2010 | L 7-59 |
| L 21-31 | 11/13/2010 | Southern Miss (6-5) | 9/17/2010 | L 16-31 at |
| 0-2 | 11-11 | 0-2 |
|
| 11-3 | — | 0 | (1 Common Ops) | 0 | Kentucky | 6-7 |
| W 10-6 vs | 12/31/2010 | Georgia (5-6) | 10/23/2010 | L 31-44 |
|
| 11-3 | — | 0 | (1 Common Ops) | 0 | Louisiana Tech | 5-7 |
| L 21-31 | 11/13/2010 | Southern Miss (6-5) | 9/25/2010 | L 12-13 |
|
| 11-3 | — | 0 | (2 Common Ops) | 0 | Louisville | 7-6 |
| L 21-31 | 11/13/2010 | Southern Miss (7-4) | 12/21/2010 | W 31-28 vs |
| W 37-17 at | 11/27/2010 | Memphis (1-9) | 10/9/2010 | W 56-0 |
| 1-1 | 8-13 | 2-0 |
|
| 10-3 | — | 1 | (6 Common Ops) | 0 | Marshall | 5-6 |
| L 21-31 | 11/13/2010 | Southern Miss (6-5) | 10/2/2010 | L 16-41 at |
| W 49-35 | 10/30/2010 | East Carolina (5-6) | 10/23/2010 | L 10-37 at |
| W 42-7 | 10/6/2010 | UAB (4-6) | 11/6/2010 | W 31-17 at |
| W 37-17 at | 11/27/2010 | Memphis (1-9) | 11/13/2010 | W 28-13 |
| W 17-7 | 12/4/2010 | SMU (6-6) | 11/20/2010 | L 17-31 at |
| W 61-14 at | 11/20/2010 | Tulane (4-6) | 11/27/2010 | W 38-23 |
| 5-1 | 26-38 | 3-3 |
|
| 11-3 | — | 0 | (2 Common Ops) | 0 | Maryland | 9-4 |
| L 21-28 | 9/11/2010 | North Carolina State (8-3) | 11/27/2010 | W 38-31 |
| W 49-35 | 10/30/2010 | East Carolina (6-5) | 12/29/2010 | W 51-20 vs |
| 1-1 | 14-8 | 2-0 |
|
| 10-3 | — | 1 | (5 Common Ops) | 0 | Memphis | 1-10 |
| W 42-7 | 10/6/2010 | UAB (3-7) | 11/20/2010 | L 15-31 at |
| W 35-14 at | 10/13/2010 | Marshall (4-6) | 11/13/2010 | L 13-28 at |
| W 49-35 | 10/30/2010 | East Carolina (5-6) | 9/11/2010 | L 27-49 at |
| W 40-33 at | 11/5/2010 | Houston (4-6) | 10/30/2010 | L 17-56 |
| L 21-31 | 11/13/2010 | Southern Miss (6-5) | 10/16/2010 | L 19-41 |
| 4-1 | 22-30 | 0-5 |
|
| 11-3 | — | 0 | (1 Common Ops) | 0 | Miami-Ohio | 10-4 |
| W 24-10 at | 9/18/2010 | Buffalo (2-8) | 10/30/2010 | W 21-9 at |
|
| 11-3 | — | 0 | (1 Common Ops) | 0 | Middle Tenn State | 6-7 |
| W 37-17 at | 11/27/2010 | Memphis (0-10) | 9/18/2010 | L 17-24 at |
|
| 11-3 | — | 0 | (1 Common Ops) | 0 | Minnesota | 3-9 |
| W 38-7 | 9/4/2010 | South Dakota (0-0) | 9/11/2010 | L 38-41 |
|
| 11-3 | — | 0 | (1 Common Ops) | 0 | Mississippi | 4-8 |
| W 61-14 at | 11/20/2010 | Tulane (4-6) | 9/11/2010 | W 27-13 at |
|
| 11-3 | — | 0 | (4 Common Ops) | 0 | Mississippi State | 9-4 |
| W 42-7 | 10/6/2010 | UAB (4-6) | 10/23/2010 | W 29-24 |
| W 40-33 at | 11/5/2010 | Houston (5-5) | 10/9/2010 | W 47-24 at |
| W 37-17 at | 11/27/2010 | Memphis (1-9) | 9/4/2010 | W 49-7 |
| W 10-6 vs | 12/31/2010 | Georgia (6-5) | 9/25/2010 | W 24-12 |
| 4-0 | 16-25 | 4-0 |
|
| 11-3 | — | 0 | (1 Common Ops) | 0 | Missouri | 10-3 |
| L 13-17 at | 9/25/2010 | Kansas State (6-5) | 11/13/2010 | W 38-28 |
|
| 11-3 | — | 0 | (1 Common Ops) | 0 | Missouri State | 0-1 |
| L 13-17 at | 9/25/2010 | Kansas State (5-6) | 9/11/2010 | L 24-48 at |
|
| 11-3 | — | 0 | (2 Common Ops) | 0 | Navy | 9-4 |
| W 49-35 | 10/30/2010 | East Carolina (6-5) | 11/6/2010 | W 76-35 at |
| W 17-7 | 12/4/2010 | SMU (7-5) | 10/16/2010 | W 28-21 |
| 2-0 | 13-10 | 2-0 |
|
| 11-3 | — | 0 | (1 Common Ops) | 0 | Nebraska | 10-4 |
| L 13-17 at | 9/25/2010 | Kansas State (6-5) | 10/7/2010 | W 48-13 at |
|
| 11-3 | — | 0 | (2 Common Ops) | 0 | North Carolina | 8-5 |
| L 21-28 | 9/11/2010 | North Carolina State (7-4) | 11/20/2010 | L 25-29 |
| W 49-35 | 10/30/2010 | East Carolina (6-5) | 10/2/2010 | W 42-17 |
| 1-1 | 13-9 | 1-1 |
|
| 11-2 | — | 0 | (1 Common Ops) | 1 | North Carolina State | 8-4 |
| W 49-35 | 10/30/2010 | East Carolina (5-6) | 10/16/2010 | L 27-33 1 at |
|
| 11-3 | — | 0 | (2 Common Ops) | 0 | North Texas | 3-9 |
| L 13-17 at | 9/25/2010 | Kansas State (5-6) | 11/27/2010 | L 41-49 |
| W 41-14 | 10/23/2010 | Rice (3-7) | 9/11/2010 | L 31-32 |
| 1-1 | 8-13 | 0-2 |
|
| 11-3 | — | 0 | (1 Common Ops) | 0 | Northern Illinois | 11-3 |
| W 24-10 at | 9/18/2010 | Buffalo (2-8) | 10/16/2010 | W 45-14 |
|
| 11-3 | — | 0 | (1 Common Ops) | 0 | Northwestern | 7-6 |
| W 41-14 | 10/23/2010 | Rice (4-6) | 9/18/2010 | W 30-13 at |
|
| 11-3 | — | 0 | (2 Common Ops) | 0 | Ohio | 8-5 |
| W 24-10 at | 9/18/2010 | Buffalo (2-8) | 11/4/2010 | W 34-17 |
| W 35-14 at | 10/13/2010 | Marshall (4-6) | 9/25/2010 | L 23-24 at |
| 2-0 | 6-14 | 1-1 |
|
| 11-3 | — | 0 | (1 Common Ops) | 0 | Ohio State | 12-1 |
| W 35-14 at | 10/13/2010 | Marshall (5-5) | 9/2/2010 | W 45-7 |
|
| 11-3 | — | 0 | (1 Common Ops) | 0 | Oklahoma State | 11-2 |
| L 13-17 at | 9/25/2010 | Kansas State (6-5) | 10/30/2010 | W 24-14 at |
|
| 11-3 | — | 0 | (1 Common Ops) | 0 | Prairie View | 0-1 |
| L 21-31 | 11/13/2010 | Southern Miss (6-5) | 9/11/2010 | L 7-34 at |
|
| 11-3 | — | 0 | (1 Common Ops) | 0 | Rhode Island | 0-1 |
| W 24-10 at | 9/18/2010 | Buffalo (1-9) | 9/2/2010 | L 0-31 at |
|
| 10-3 | — | 1 | (5 Common Ops) | 0 | Rice | 4-7 |
| W 42-7 | 10/6/2010 | UAB (4-6) | 11/27/2010 | W 28-23 |
| W 49-35 | 10/30/2010 | East Carolina (6-5) | 11/20/2010 | W 62-38 |
| W 40-33 at | 11/5/2010 | Houston (5-5) | 10/16/2010 | W 34-31 |
| W 61-14 at | 11/20/2010 | Tulane (3-7) | 11/13/2010 | L 49-54 at |
| W 17-7 | 12/4/2010 | SMU (6-6) | 10/2/2010 | L 31-42 |
| 5-0 | 24-29 | 3-2 |
|
| 11-3 | — | 0 | (1 Common Ops) | 0 | Rutgers | 4-8 |
| W 61-14 at | 11/20/2010 | Tulane (3-7) | 10/2/2010 | L 14-17 |
|
| 10-3 | — | 1 | (6 Common Ops) | 0 | SMU | 7-6 |
| W 42-7 | 10/6/2010 | UAB (4-6) | 9/11/2010 | W 28-7 |
| W 35-14 at | 10/13/2010 | Marshall (5-5) | 11/20/2010 | W 31-17 |
| W 41-14 | 10/23/2010 | Rice (4-6) | 10/2/2010 | W 42-31 at |
| W 49-35 | 10/30/2010 | East Carolina (6-5) | 11/26/2010 | W 45-38 1 at |
| W 40-33 at | 11/5/2010 | Houston (4-6) | 10/23/2010 | L 20-45 |
| W 61-14 at | 11/20/2010 | Tulane (4-6) | 10/30/2010 | W 31-17 at |
| 6-0 | 27-34 | 5-1 |
|
| 11-3 | — | 0 | (2 Common Ops) | 0 | South Carolina | 9-5 |
| L 21-31 | 11/13/2010 | Southern Miss (7-4) | 9/2/2010 | W 41-13 |
| W 10-6 vs | 12/31/2010 | Georgia (6-5) | 9/11/2010 | W 17-6 |
| 1-1 | 13-9 | 2-0 |
|
| 11-3 | — | 0 | (1 Common Ops) | 0 | Southeastern Louisiana | 0-2 |
| W 61-14 at | 11/20/2010 | Tulane (3-7) | 9/2/2010 | L 21-27 at |
|
| 11-2 | — | 0 | (6 Common Ops) | 1 | Southern Miss | 7-5 |
| W 35-14 at | 10/13/2010 | Marshall (5-5) | 10/2/2010 | W 41-16 |
| W 49-35 | 10/30/2010 | East Carolina (5-6) | 10/9/2010 | L 43-44 |
| W 37-17 at | 11/27/2010 | Memphis (1-9) | 10/16/2010 | W 41-19 at |
| W 42-7 | 10/6/2010 | UAB (3-7) | 10/30/2010 | L 49-50 2 |
| W 61-14 at | 11/20/2010 | Tulane (4-6) | 11/6/2010 | W 46-30 at |
| W 40-33 at | 11/5/2010 | Houston (5-5) | 11/20/2010 | W 59-41 |
| 6-0 | 23-38 | 4-2 |
|
| 11-3 | — | 0 | (1 Common Ops) | 0 | Syracuse | 8-5 |
| L 13-17 at | 9/25/2010 | Kansas State (6-5) | 12/30/2010 | W 36-34 vs |
|
| 11-3 | — | 0 | (1 Common Ops) | 0 | TCU | 13-0 |
| W 17-7 | 12/4/2010 | SMU (7-5) | 9/24/2010 | W 41-24 at |
|
| 11-3 | — | 0 | (1 Common Ops) | 0 | Temple | 8-4 |
| W 24-10 at | 9/18/2010 | Buffalo (2-8) | 10/23/2010 | W 42-0 at |
|
| 11-3 | — | 0 | (3 Common Ops) | 0 | Tennessee | 6-7 |
| W 42-7 | 10/6/2010 | UAB (4-6) | 9/25/2010 | W 32-29 2 |
| W 37-17 at | 11/27/2010 | Memphis (1-9) | 11/6/2010 | W 50-14 at |
| W 10-6 vs | 12/31/2010 | Georgia (5-6) | 10/9/2010 | L 14-41 at |
| 3-0 | 10-21 | 2-1 |
|
| 11-3 | — | 0 | (2 Common Ops) | 0 | Texas | 5-7 |
| L 13-17 at | 9/25/2010 | Kansas State (5-6) | 11/6/2010 | L 14-39 at |
| W 41-14 | 10/23/2010 | Rice (4-6) | 9/4/2010 | W 34-17 at |
| 1-1 | 9-12 | 1-1 |
|
| 11-3 | — | 0 | (1 Common Ops) | 0 | Texas State | 0-1 |
| W 40-33 at | 11/5/2010 | Houston (4-6) | 9/4/2010 | L 28-68 at |
|
| 11-3 | — | 0 | (2 Common Ops) | 0 | Texas Tech | 8-5 |
| W 40-33 at | 11/5/2010 | Houston (5-5) | 11/27/2010 | W 35-20 |
| W 17-7 | 12/4/2010 | SMU (7-5) | 9/5/2010 | W 35-27 |
| 2-0 | 12-10 | 2-0 |
|
| 11-3 | — | 0 | (1 Common Ops) | 0 | Troy | 8-5 |
| W 42-7 | 10/6/2010 | UAB (3-7) | 9/18/2010 | L 33-34 at |
|
| 10-3 | — | 1 | (5 Common Ops) | 0 | Tulane | 4-7 |
| W 40-33 at | 11/5/2010 | Houston (4-6) | 9/25/2010 | L 23-42 at |
| W 17-7 | 12/4/2010 | SMU (6-6) | 10/30/2010 | L 17-31 |
| L 21-31 | 11/13/2010 | Southern Miss (6-5) | 11/6/2010 | L 30-46 |
| W 41-14 | 10/23/2010 | Rice (4-6) | 11/13/2010 | W 54-49 |
| W 35-14 at | 10/13/2010 | Marshall (4-6) | 11/27/2010 | L 23-38 at |
| 4-1 | 24-29 | 1-4 |
|
| 11-3 | — | 0 | (7 Common Ops) | 0 | Tulsa | 10-3 |
| W 41-14 | 10/23/2010 | Rice (4-6) | 11/6/2010 | W 64-27 |
| W 49-35 | 10/30/2010 | East Carolina (5-6) | 9/5/2010 | L 49-51 at |
| W 40-33 at | 11/5/2010 | Houston (5-5) | 11/13/2010 | W 28-25 at |
| L 21-31 | 11/13/2010 | Southern Miss (7-4) | 11/26/2010 | W 56-50 |
| W 61-14 at | 11/20/2010 | Tulane (4-6) | 10/16/2010 | W 52-24 |
| W 37-17 at | 11/27/2010 | Memphis (1-9) | 10/2/2010 | W 48-7 at |
| W 17-7 | 12/4/2010 | SMU (6-6) | 10/9/2010 | L 18-21 at |
| 6-1 | 32-42 | 5-2 |
|
| 10-3 | — | 1 | (6 Common Ops) | 0 | UAB | 4-7 |
| W 17-7 | 12/4/2010 | SMU (6-6) | 9/11/2010 | L 7-28 at |
| L 21-31 | 11/13/2010 | Southern Miss (7-4) | 10/30/2010 | W 50-49 2 at |
| W 35-14 at | 10/13/2010 | Marshall (4-6) | 11/6/2010 | L 17-31 |
| W 49-35 | 10/30/2010 | East Carolina (5-6) | 11/11/2010 | L 42-54 |
| W 37-17 at | 11/27/2010 | Memphis (1-9) | 11/20/2010 | W 31-15 |
| W 41-14 | 10/23/2010 | Rice (3-7) | 11/27/2010 | L 23-28 at |
| 5-1 | 26-38 | 2-4 |
|
| 11-3 | — | 0 | (2 Common Ops) | 0 | UCLA | 4-8 |
| L 13-17 at | 9/25/2010 | Kansas State (5-6) | 9/4/2010 | L 22-31 at |
| W 40-33 at | 11/5/2010 | Houston (5-5) | 9/18/2010 | W 31-13 |
| 1-1 | 10-11 | 1-1 |
|
| 11-3 | — | 0 | (1 Common Ops) | 0 | UL Lafayette | 3-9 |
| W 10-6 vs | 12/31/2010 | Georgia (5-6) | 9/4/2010 | L 7-55 at |
|
| 11-3 | — | 0 | (7 Common Ops) | 0 | UTEP | 6-7 |
| W 42-7 | 10/6/2010 | UAB (3-7) | 10/16/2010 | L 6-21 at |
| W 35-14 at | 10/13/2010 | Marshall (4-6) | 10/30/2010 | L 12-16 at |
| W 41-14 | 10/23/2010 | Rice (4-6) | 10/9/2010 | W 44-24 |
| W 40-33 at | 11/5/2010 | Houston (4-6) | 9/10/2010 | L 24-54 at |
| W 61-14 at | 11/20/2010 | Tulane (3-7) | 10/23/2010 | L 24-34 |
| W 37-17 at | 11/27/2010 | Memphis (1-9) | 9/25/2010 | W 16-13 |
| W 17-7 | 12/4/2010 | SMU (7-5) | 11/6/2010 | W 28-14 |
| 7-0 | 26-46 | 3-4 |
|
| 11-3 | — | 0 | (1 Common Ops) | 0 | Vanderbilt | 2-10 |
| W 10-6 vs | 12/31/2010 | Georgia (5-6) | 10/16/2010 | L 0-43 at |
|
| 11-3 | — | 0 | (2 Common Ops) | 0 | Virginia Tech | 11-3 |
| L 21-28 | 9/11/2010 | North Carolina State (8-3) | 10/2/2010 | W 41-30 at |
| W 49-35 | 10/30/2010 | East Carolina (6-5) | 9/18/2010 | W 49-27 |
| 1-1 | 14-8 | 2-0 |
|
| 11-3 | — | 0 | (1 Common Ops) | 0 | Wake Forest | 3-9 |
| L 21-28 | 9/11/2010 | North Carolina State (7-4) | 11/13/2010 | L 3-38 at |
|
| 11-3 | — | 0 | (1 Common Ops) | 0 | Washington State | 2-10 |
| W 17-7 | 12/4/2010 | SMU (6-6) | 9/18/2010 | L 21-35 at |
|
| 11-3 | — | 0 | (2 Common Ops) | 0 | West Virginia | 9-4 |
| L 21-28 | 9/11/2010 | North Carolina State (7-4) | 12/28/2010 | L 7-23 vs |
| W 35-14 at | 10/13/2010 | Marshall (5-5) | 9/10/2010 | W 24-21 1 at |
| 1-1 | 12-9 | 1-1 |
|
| 11-3 | — | 0 | (1 Common Ops) | 0 | Western Carolina | 0-1 |
| L 21-28 | 9/11/2010 | North Carolina State (7-4) | 9/4/2010 | L 7-48 at |
|