| 11-3 | — | 0 | (1 Common Ops) | 0 | Alabama | 9-3 |
| W 44-7 | 10/23/2010 | Duke (3-7) | 9/18/2010 | W 62-13 at |
|
| 11-3 | — | 0 | (1 Common Ops) | 0 | Arizona | 7-6 |
| L 12-40 vs | 1/3/2011 | Stanford (10-1) | 11/6/2010 | L 17-42 at |
|
| 11-3 | — | 0 | (1 Common Ops) | 0 | Arizona State | 6-6 |
| L 12-40 vs | 1/3/2011 | Stanford (10-1) | 11/13/2010 | L 13-17 |
|
| 11-3 | — | 0 | (1 Common Ops) | 0 | Army | 7-6 |
| W 44-7 | 10/23/2010 | Duke (3-7) | 9/25/2010 | W 35-21 at |
|
| 11-3 | — | 0 | (1 Common Ops) | 0 | Ball State | 4-8 |
| W 45-21 | 10/9/2010 | Central Michigan (3-7) | 10/2/2010 | W 31-17 at |
|
| 10-3 | — | 1 | (5 Common Ops) | 0 | Boston College | 7-5 |
| W 41-30 at | 10/2/2010 | North Carolina State (8-3) | 10/9/2010 | L 17-44 at |
| W 44-33 vs | 12/4/2010 | Florida State (9-3) | 10/16/2010 | L 19-24 at |
| W 52-21 | 10/16/2010 | Wake Forest (3-7) | 11/6/2010 | W 23-13 at |
| W 44-7 | 10/23/2010 | Duke (3-7) | 11/13/2010 | W 21-16 at |
| W 37-7 | 11/27/2010 | Virginia (4-6) | 11/20/2010 | W 17-13 |
| 5-0 | 27-26 | 3-2 |
|
| 11-3 | — | 0 | (1 Common Ops) | 0 | Bowling Green | 2-10 |
| W 45-21 | 10/9/2010 | Central Michigan (3-7) | 10/30/2010 | W 17-14 at |
|
| 11-3 | — | 0 | (1 Common Ops) | 0 | BYU | 7-6 |
| W 44-33 vs | 12/4/2010 | Florida State (9-3) | 9/18/2010 | L 10-34 at |
|
| 11-3 | — | 0 | (1 Common Ops) | 0 | California | 5-7 |
| L 12-40 vs | 1/3/2011 | Stanford (10-1) | 11/20/2010 | L 14-48 |
|
| 11-3 | — | 0 | (1 Common Ops) | 0 | Cincinnati | 4-8 |
| W 41-30 at | 10/2/2010 | North Carolina State (8-3) | 9/16/2010 | L 19-30 at |
|
| 11-3 | — | 0 | (7 Common Ops) | 0 | Clemson | 6-7 |
| W 31-17 at | 11/20/2010 | Miami-Florida (6-5) | 10/2/2010 | L 21-30 |
| W 26-10 at | 11/13/2010 | North Carolina (7-4) | 10/9/2010 | L 16-21 at |
| W 28-21 | 11/4/2010 | Georgia Tech (6-5) | 10/23/2010 | W 27-13 |
| W 19-0 at | 9/25/2010 | Boston College (6-5) | 10/30/2010 | L 10-16 at |
| W 41-30 at | 10/2/2010 | North Carolina State (9-2) | 11/6/2010 | W 14-13 |
| W 44-33 vs | 12/4/2010 | Florida State (9-3) | 11/13/2010 | L 13-16 at |
| W 52-21 | 10/16/2010 | Wake Forest (3-7) | 11/20/2010 | W 30-10 at |
| 7-0 | 46-31 | 3-4 |
|
| 10-3 | — | 1 | (6 Common Ops) | 0 | Duke | 3-8 |
| W 52-21 | 10/16/2010 | Wake Forest (2-8) | 9/11/2010 | L 48-54 at |
| W 31-17 at | 11/20/2010 | Miami-Florida (6-5) | 10/16/2010 | L 13-28 |
| W 37-7 | 11/27/2010 | Virginia (4-6) | 11/6/2010 | W 56-48 |
| W 19-0 at | 9/25/2010 | Boston College (6-5) | 11/13/2010 | L 16-21 |
| W 28-21 | 11/4/2010 | Georgia Tech (5-6) | 11/20/2010 | L 20-30 at |
| W 26-10 at | 11/13/2010 | North Carolina (7-4) | 11/27/2010 | L 19-24 |
| 6-0 | 30-34 | 1-5 |
|
| 10-3 | — | 1 | (2 Common Ops) | 0 | East Carolina | 6-6 |
| W 26-10 at | 11/13/2010 | North Carolina (7-4) | 10/2/2010 | L 17-42 at |
| W 41-30 at | 10/2/2010 | North Carolina State (9-2) | 10/16/2010 | W 33-27 1 |
| 2-0 | 16-6 | 1-1 |
|
| 11-3 | — | 0 | (2 Common Ops) | 0 | Eastern Michigan | 2-10 |
| W 45-21 | 10/9/2010 | Central Michigan (2-8) | 9/18/2010 | L 14-52 |
| W 37-7 | 11/27/2010 | Virginia (3-7) | 10/23/2010 | L 21-48 at |
| 2-0 | 5-15 | 0-2 |
|
| 11-3 | — | 0 | (1 Common Ops) | 0 | Elon | 0-1 |
| W 44-7 | 10/23/2010 | Duke (2-8) | 9/4/2010 | L 27-41 at |
|
| 11-3 | — | 0 | (1 Common Ops) | 0 | Florida | 8-5 |
| W 44-33 vs | 12/4/2010 | Florida State (9-3) | 11/27/2010 | L 7-31 at |
|
| 11-3 | — | 0 | (1 Common Ops) | 0 | Florida A&M | 0-1 |
| W 31-17 at | 11/20/2010 | Miami-Florida (6-5) | 9/2/2010 | L 0-45 at |
|
| 10-3 | — | 1 | (6 Common Ops) | 0 | Florida State | 10-3 |
| W 52-21 | 10/16/2010 | Wake Forest (3-7) | 9/25/2010 | W 31-0 |
| W 37-7 | 11/27/2010 | Virginia (4-6) | 10/2/2010 | W 34-14 at |
| W 31-17 at | 11/20/2010 | Miami-Florida (7-4) | 10/9/2010 | W 45-17 at |
| W 19-0 at | 9/25/2010 | Boston College (7-4) | 10/16/2010 | W 24-19 |
| W 41-30 at | 10/2/2010 | North Carolina State (8-3) | 10/28/2010 | L 24-28 at |
| W 26-10 at | 11/13/2010 | North Carolina (7-4) | 11/6/2010 | L 35-37 |
| 6-0 | 36-28 | 4-2 |
|
| 11-3 | — | 0 | (1 Common Ops) | 0 | Fresno State | 8-5 |
| L 30-33 vs | 9/6/2010 | Boise State (10-1) | 11/19/2010 | L 0-51 at |
|
| 11-3 | — | 0 | (1 Common Ops) | 0 | Georgia | 6-7 |
| W 28-21 | 11/4/2010 | Georgia Tech (6-5) | 11/27/2010 | W 42-34 |
|
| 10-3 | — | 1 | (6 Common Ops) | 0 | Georgia Tech | 6-6 |
| W 26-10 at | 11/13/2010 | North Carolina (8-3) | 9/18/2010 | W 30-24 at |
| W 41-30 at | 10/2/2010 | North Carolina State (8-3) | 9/25/2010 | L 28-45 |
| W 52-21 | 10/16/2010 | Wake Forest (3-7) | 10/2/2010 | W 24-20 at |
| W 37-7 | 11/27/2010 | Virginia (4-6) | 10/9/2010 | W 33-21 |
| W 31-17 at | 11/20/2010 | Miami-Florida (6-5) | 11/13/2010 | L 10-35 |
| W 44-7 | 10/23/2010 | Duke (3-7) | 11/20/2010 | W 30-20 |
| 6-0 | 32-31 | 4-2 |
|
| 11-3 | — | 0 | (1 Common Ops) | 0 | Hampton | 0-1 |
| W 45-21 | 10/9/2010 | Central Michigan (2-8) | 9/2/2010 | L 0-33 at |
|
| 11-3 | — | 0 | (1 Common Ops) | 0 | Hawaii | 10-4 |
| L 30-33 vs | 9/6/2010 | Boise State (10-1) | 11/6/2010 | L 7-42 at |
|
| 11-3 | — | 0 | (1 Common Ops) | 0 | Idaho | 6-7 |
| L 30-33 vs | 9/6/2010 | Boise State (10-1) | 11/12/2010 | L 14-52 |
|
| 11-3 | — | 0 | (1 Common Ops) | 0 | Kansas | 3-9 |
| W 28-21 | 11/4/2010 | Georgia Tech (6-5) | 9/11/2010 | W 28-25 |
|
| 11-3 | — | 0 | (1 Common Ops) | 0 | Kent State | 5-7 |
| W 19-0 at | 9/25/2010 | Boston College (6-5) | 9/11/2010 | L 13-26 at |
|
| 11-3 | — | 0 | (1 Common Ops) | 0 | Louisiana Tech | 5-7 |
| L 30-33 vs | 9/6/2010 | Boise State (10-1) | 10/26/2010 | L 20-49 at |
|
| 11-3 | — | 0 | (1 Common Ops) | 0 | LSU | 11-2 |
| W 26-10 at | 11/13/2010 | North Carolina (8-3) | 9/4/2010 | W 30-24 vs |
|
| 11-3 | — | 0 | (1 Common Ops) | 0 | Marshall | 5-7 |
| W 49-27 | 9/18/2010 | East Carolina (5-6) | 10/23/2010 | L 10-37 at |
|
| 11-3 | — | 0 | (8 Common Ops) | 0 | Maryland | 9-4 |
| W 44-7 | 10/23/2010 | Duke (3-7) | 10/2/2010 | W 21-16 |
| W 19-0 at | 9/25/2010 | Boston College (7-4) | 10/23/2010 | W 24-21 at |
| W 52-21 | 10/16/2010 | Wake Forest (3-7) | 10/30/2010 | W 62-14 |
| W 31-17 at | 11/20/2010 | Miami-Florida (6-5) | 11/6/2010 | L 20-26 at |
| W 37-7 | 11/27/2010 | Virginia (4-6) | 11/13/2010 | W 42-23 at |
| W 44-33 vs | 12/4/2010 | Florida State (9-3) | 11/20/2010 | L 16-30 |
| W 41-30 at | 10/2/2010 | North Carolina State (9-2) | 11/27/2010 | W 38-31 |
| W 49-27 | 9/18/2010 | East Carolina (6-5) | 12/29/2010 | W 51-20 vs |
| 8-0 | 47-39 | 6-2 |
|
| 11-3 | — | 0 | (1 Common Ops) | 0 | Memphis | 1-11 |
| W 49-27 | 9/18/2010 | East Carolina (5-6) | 9/11/2010 | L 27-49 at |
|
| 10-3 | — | 1 | (5 Common Ops) | 0 | Miami-Florida | 7-5 |
| W 44-33 vs | 12/4/2010 | Florida State (9-3) | 10/9/2010 | L 17-45 |
| W 44-7 | 10/23/2010 | Duke (3-7) | 10/16/2010 | W 28-13 at |
| W 26-10 at | 11/13/2010 | North Carolina (8-3) | 10/23/2010 | W 33-10 |
| W 37-7 | 11/27/2010 | Virginia (3-7) | 10/30/2010 | L 19-24 at |
| W 28-21 | 11/4/2010 | Georgia Tech (6-5) | 11/13/2010 | W 35-10 at |
| 5-0 | 29-25 | 3-2 |
|
| 11-3 | — | 0 | (1 Common Ops) | 0 | Miami-Ohio | 10-4 |
| W 45-21 | 10/9/2010 | Central Michigan (3-7) | 10/16/2010 | W 27-20 at |
|
| 11-3 | — | 0 | (1 Common Ops) | 0 | Middle Tenn State | 6-7 |
| W 28-21 | 11/4/2010 | Georgia Tech (5-6) | 10/16/2010 | L 14-42 at |
|
| 11-3 | — | 0 | (4 Common Ops) | 0 | Navy | 9-4 |
| W 52-21 | 10/16/2010 | Wake Forest (3-7) | 10/9/2010 | W 28-27 at |
| W 44-7 | 10/23/2010 | Duke (2-8) | 10/30/2010 | L 31-34 |
| W 49-27 | 9/18/2010 | East Carolina (6-5) | 11/6/2010 | W 76-35 at |
| W 45-21 | 10/9/2010 | Central Michigan (3-7) | 11/13/2010 | W 38-37 |
| 4-0 | 14-27 | 3-1 |
|
| 11-3 | — | 0 | (2 Common Ops) | 0 | Nevada | 13-1 |
| L 30-33 vs | 9/6/2010 | Boise State (11-0) | 11/26/2010 | W 34-31 1 |
| W 19-0 at | 9/25/2010 | Boston College (7-4) | 1/9/2011 | W 20-13 vs |
| 1-1 | 18-4 | 2-0 |
|
| 11-3 | — | 0 | (1 Common Ops) | 0 | New Mexico State | 2-10 |
| L 30-33 vs | 9/6/2010 | Boise State (10-1) | 10/2/2010 | L 0-59 |
|
| 10-3 | — | 1 | (7 Common Ops) | 0 | North Carolina | 8-4 |
| W 28-21 | 11/4/2010 | Georgia Tech (5-6) | 9/18/2010 | L 24-30 |
| W 49-27 | 9/18/2010 | East Carolina (6-5) | 10/2/2010 | W 42-17 |
| W 37-7 | 11/27/2010 | Virginia (4-6) | 10/16/2010 | W 44-10 at |
| W 31-17 at | 11/20/2010 | Miami-Florida (6-5) | 10/23/2010 | L 10-33 at |
| W 44-33 vs | 12/4/2010 | Florida State (10-2) | 11/6/2010 | W 37-35 at |
| W 41-30 at | 10/2/2010 | North Carolina State (8-3) | 11/20/2010 | L 25-29 |
| W 44-7 | 10/23/2010 | Duke (3-7) | 11/27/2010 | W 24-19 at |
| 7-0 | 42-34 | 4-3 |
|
| 10-3 | — | 1 | (6 Common Ops) | 0 | North Carolina State | 9-3 |
| W 28-21 | 11/4/2010 | Georgia Tech (6-5) | 9/25/2010 | W 45-28 at |
| W 19-0 at | 9/25/2010 | Boston College (7-4) | 10/9/2010 | W 44-17 |
| W 49-27 | 9/18/2010 | East Carolina (5-6) | 10/16/2010 | L 27-33 1 at |
| W 44-33 vs | 12/4/2010 | Florida State (10-2) | 10/28/2010 | W 28-24 |
| W 52-21 | 10/16/2010 | Wake Forest (3-7) | 11/13/2010 | W 38-3 |
| W 26-10 at | 11/13/2010 | North Carolina (8-3) | 11/20/2010 | W 29-25 at |
| 6-0 | 39-27 | 5-1 |
|
| 11-3 | — | 0 | (1 Common Ops) | 0 | Northern Illinois | 11-3 |
| W 45-21 | 10/9/2010 | Central Michigan (3-7) | 10/23/2010 | W 33-7 |
|
| 11-3 | — | 0 | (1 Common Ops) | 0 | Northwestern | 7-6 |
| W 45-21 | 10/9/2010 | Central Michigan (3-7) | 9/25/2010 | W 30-25 |
|
| 11-3 | — | 0 | (3 Common Ops) | 0 | Notre Dame | 8-5 |
| L 12-40 vs | 1/3/2011 | Stanford (10-1) | 9/25/2010 | L 14-37 |
| W 19-0 at | 9/25/2010 | Boston College (7-4) | 10/2/2010 | W 31-13 at |
| W 31-17 at | 11/20/2010 | Miami-Florida (7-4) | 12/31/2010 | W 33-17 vs |
| 2-1 | 24-9 | 2-1 |
|
| 11-3 | — | 0 | (1 Common Ops) | 0 | Ohio State | 12-1 |
| W 31-17 at | 11/20/2010 | Miami-Florida (7-4) | 9/11/2010 | W 36-24 |
|
| 11-3 | — | 0 | (1 Common Ops) | 0 | Oklahoma | 12-2 |
| W 44-33 vs | 12/4/2010 | Florida State (10-2) | 9/11/2010 | W 47-17 |
|
| 11-3 | — | 0 | (1 Common Ops) | 0 | Oregon | 12-1 |
| L 12-40 vs | 1/3/2011 | Stanford (11-0) | 10/2/2010 | W 52-31 |
|
| 11-3 | — | 0 | (2 Common Ops) | 0 | Oregon State | 5-7 |
| L 30-33 vs | 9/6/2010 | Boise State (10-1) | 9/25/2010 | L 24-37 at |
| L 12-40 vs | 1/3/2011 | Stanford (10-1) | 11/27/2010 | L 0-38 at |
| 0-2 | 20-2 | 0-2 |
|
| 11-3 | — | 0 | (1 Common Ops) | 0 | Pittsburgh | 8-5 |
| W 31-17 at | 11/20/2010 | Miami-Florida (6-5) | 9/23/2010 | L 3-31 |
|
| 11-3 | — | 0 | (1 Common Ops) | 0 | Presbyterian | 0-2 |
| W 52-21 | 10/16/2010 | Wake Forest (2-8) | 9/2/2010 | L 13-53 at |
|
| 11-3 | — | 0 | (1 Common Ops) | 0 | Rice | 4-8 |
| W 49-27 | 9/18/2010 | East Carolina (6-5) | 11/20/2010 | W 62-38 |
|
| 11-3 | — | 0 | (1 Common Ops) | 0 | Richmond | 0-1 |
| W 37-7 | 11/27/2010 | Virginia (3-7) | 9/4/2010 | L 13-34 at |
|
| 11-3 | — | 0 | (1 Common Ops) | 0 | Rutgers | 4-8 |
| W 26-10 at | 11/13/2010 | North Carolina (7-4) | 9/25/2010 | L 13-17 |
|
| 11-3 | — | 0 | (1 Common Ops) | 0 | Sacramento State | 0-1 |
| L 12-40 vs | 1/3/2011 | Stanford (10-1) | 9/4/2010 | L 17-52 at |
|
| 11-3 | — | 0 | (1 Common Ops) | 0 | Samford | 0-1 |
| W 44-33 vs | 12/4/2010 | Florida State (9-3) | 9/4/2010 | L 6-59 at |
|
| 11-3 | — | 0 | (1 Common Ops) | 0 | San Jose State | 1-12 |
| L 30-33 vs | 9/6/2010 | Boise State (10-1) | 10/16/2010 | L 0-48 |
|
| 11-3 | — | 0 | (1 Common Ops) | 0 | SMU | 7-7 |
| W 49-27 | 9/18/2010 | East Carolina (6-5) | 11/26/2010 | W 45-38 1 at |
|
| 11-3 | — | 0 | (1 Common Ops) | 0 | South Carolina | 9-5 |
| W 44-33 vs | 12/4/2010 | Florida State (9-3) | 12/31/2010 | L 17-26 vs |
|
| 11-3 | — | 0 | (1 Common Ops) | 0 | South Carolina State | 0-1 |
| W 28-21 | 11/4/2010 | Georgia Tech (5-6) | 9/4/2010 | L 10-41 at |
|
| 11-3 | — | 0 | (1 Common Ops) | 0 | South Florida | 8-5 |
| W 31-17 at | 11/20/2010 | Miami-Florida (7-4) | 11/27/2010 | W 23-20 1 at |
|
| 11-3 | — | 0 | (2 Common Ops) | 0 | Southern California | 8-5 |
| W 37-7 | 11/27/2010 | Virginia (4-6) | 9/11/2010 | W 17-7 |
| L 12-40 vs | 1/3/2011 | Stanford (10-1) | 10/9/2010 | L 35-37 at |
| 1-1 | 14-7 | 1-1 |
|
| 11-3 | — | 0 | (1 Common Ops) | 0 | Southern Miss | 8-5 |
| W 49-27 | 9/18/2010 | East Carolina (5-6) | 10/9/2010 | L 43-44 |
|
| 11-2 | — | 0 | (1 Common Ops) | 1 | Stanford | 11-1 |
| W 52-21 | 10/16/2010 | Wake Forest (3-7) | 9/18/2010 | W 68-24 |
|
| 11-3 | — | 0 | (1 Common Ops) | 0 | Syracuse | 8-5 |
| W 19-0 at | 9/25/2010 | Boston College (6-5) | 11/27/2010 | L 7-16 |
|
| 11-3 | — | 0 | (1 Common Ops) | 0 | Temple | 8-4 |
| W 45-21 | 10/9/2010 | Central Michigan (3-7) | 9/9/2010 | W 13-10 1 |
|
| 11-3 | — | 0 | (1 Common Ops) | 0 | Tennessee | 6-7 |
| W 26-10 at | 11/13/2010 | North Carolina (7-4) | 12/30/2010 | L 27-30 2OT vs |
|
| 11-3 | — | 0 | (2 Common Ops) | 0 | Toledo | 8-5 |
| L 30-33 vs | 9/6/2010 | Boise State (10-1) | 10/9/2010 | L 14-57 at |
| W 45-21 | 10/9/2010 | Central Michigan (3-7) | 11/26/2010 | W 42-31 |
| 1-1 | 13-8 | 1-1 |
|
| 11-3 | — | 0 | (1 Common Ops) | 0 | Tulsa | 10-3 |
| W 49-27 | 9/18/2010 | East Carolina (5-6) | 9/5/2010 | L 49-51 at |
|
| 11-3 | — | 0 | (1 Common Ops) | 0 | UAB | 4-8 |
| W 49-27 | 9/18/2010 | East Carolina (5-6) | 11/11/2010 | L 42-54 |
|
| 11-3 | — | 0 | (2 Common Ops) | 0 | UCF | 11-3 |
| W 41-30 at | 10/2/2010 | North Carolina State (8-3) | 9/11/2010 | L 21-28 |
| W 49-27 | 9/18/2010 | East Carolina (6-5) | 10/30/2010 | W 49-35 |
| 2-0 | 14-8 | 1-1 |
|
| 11-3 | — | 0 | (1 Common Ops) | 0 | UCLA | 4-8 |
| L 12-40 vs | 1/3/2011 | Stanford (10-1) | 9/11/2010 | L 0-35 |
|
| 11-3 | — | 0 | (1 Common Ops) | 0 | Utah | 10-3 |
| L 30-33 vs | 9/6/2010 | Boise State (10-1) | 12/22/2010 | L 3-26 vs |
|
| 11-3 | — | 0 | (1 Common Ops) | 0 | Utah State | 4-8 |
| L 30-33 vs | 9/6/2010 | Boise State (10-1) | 12/4/2010 | L 14-50 at |
|
| 11-3 | — | 0 | (1 Common Ops) | 0 | Vanderbilt | 2-10 |
| W 52-21 | 10/16/2010 | Wake Forest (2-8) | 11/27/2010 | L 13-34 |
|
| 10-3 | — | 1 | (6 Common Ops) | 0 | Virginia | 4-7 |
| W 44-33 vs | 12/4/2010 | Florida State (9-3) | 10/2/2010 | L 14-34 |
| W 28-21 | 11/4/2010 | Georgia Tech (5-6) | 10/9/2010 | L 21-33 at |
| W 26-10 at | 11/13/2010 | North Carolina (7-4) | 10/16/2010 | L 10-44 |
| W 31-17 at | 11/20/2010 | Miami-Florida (7-4) | 10/30/2010 | W 24-19 |
| W 44-7 | 10/23/2010 | Duke (2-8) | 11/6/2010 | L 48-56 at |
| W 19-0 at | 9/25/2010 | Boston College (6-5) | 11/20/2010 | L 13-17 at |
| 6-0 | 36-30 | 1-5 |
|
| 11-3 | — | 0 | (1 Common Ops) | 0 | VMI | 0-2 |
| W 37-7 | 11/27/2010 | Virginia (3-7) | 9/25/2010 | L 7-48 at |
|
| 10-3 | — | 1 | (6 Common Ops) | 0 | Wake Forest | 3-8 |
| W 44-7 | 10/23/2010 | Duke (3-7) | 9/11/2010 | W 54-48 |
| L 12-40 vs | 1/3/2011 | Stanford (10-1) | 9/18/2010 | L 24-68 at |
| W 44-33 vs | 12/4/2010 | Florida State (9-3) | 9/25/2010 | L 0-31 at |
| W 28-21 | 11/4/2010 | Georgia Tech (5-6) | 10/2/2010 | L 20-24 |
| W 19-0 at | 9/25/2010 | Boston College (6-5) | 11/6/2010 | L 13-23 |
| W 41-30 at | 10/2/2010 | North Carolina State (8-3) | 11/13/2010 | L 3-38 at |
| 5-1 | 41-25 | 1-5 |
|
| 11-3 | — | 0 | (1 Common Ops) | 0 | Washington | 7-6 |
| L 12-40 vs | 1/3/2011 | Stanford (10-1) | 10/30/2010 | L 0-41 |
|
| 11-3 | — | 0 | (1 Common Ops) | 0 | Washington State | 2-10 |
| L 12-40 vs | 1/3/2011 | Stanford (10-1) | 10/23/2010 | L 28-38 at |
|
| 11-3 | — | 0 | (1 Common Ops) | 0 | Weber State | 0-2 |
| W 19-0 at | 9/25/2010 | Boston College (6-5) | 9/4/2010 | L 20-38 at |
|
| 11-3 | — | 0 | (1 Common Ops) | 0 | West Virginia | 9-4 |
| W 41-30 at | 10/2/2010 | North Carolina State (8-3) | 12/28/2010 | L 7-23 vs |
|
| 11-3 | — | 0 | (1 Common Ops) | 0 | Western Carolina | 0-1 |
| W 41-30 at | 10/2/2010 | North Carolina State (8-3) | 9/4/2010 | L 7-48 at |
|
| 11-3 | — | 0 | (1 Common Ops) | 0 | Western Michigan | 6-6 |
| W 45-21 | 10/9/2010 | Central Michigan (2-8) | 11/5/2010 | L 22-26 at |
|
| 11-3 | — | 0 | (1 Common Ops) | 0 | William & Mary | 0-1 |
| W 26-10 at | 11/13/2010 | North Carolina (7-4) | 10/30/2010 | L 17-21 at |
|
| 11-3 | — | 0 | (1 Common Ops) | 0 | Wyoming | 3-9 |
| L 30-33 vs | 9/6/2010 | Boise State (10-1) | 9/18/2010 | L 6-51 |
|