11 Jan 2011 5:04pm (US Central)
| 2-10 | — | 0 | (6 Common Ops) | 0 | Akron | 1-11 |
| L 6-30 | 10/23/2010 | Kent State (3-7) | 10/9/2010 | L 17-28 at |
| L 25-49 at | 10/9/2010 | Ohio (6-5) | 10/16/2010 | L 10-38 at |
| L 7-41 | 11/26/2010 | Western Michigan (4-6) | 10/23/2010 | L 10-56 |
| L 27-28 at | 10/16/2010 | Temple (6-4) | 10/30/2010 | L 0-30 at |
| L 21-24 | 11/10/2010 | Miami-Ohio (8-4) | 11/17/2010 | L 14-19 |
| L 26-28 | 10/2/2010 | Buffalo (1-9) | 11/26/2010 | W 22-14 |
| 0-6 | 28-35 | 1-5 |
|
| 2-10 | — | 0 | (1 Common Ops) | 0 | Arizona | 7-6 |
| L 14-33 at | 11/17/2010 | Toledo (7-4) | 9/3/2010 | W 41-2 at |
|
| 2-10 | — | 0 | (1 Common Ops) | 0 | Arkansas State | 4-8 |
| L 27-30 at | 9/4/2010 | Troy (6-5) | 9/25/2010 | L 28-35 at |
|
| 2-10 | — | 0 | (2 Common Ops) | 0 | Army | 7-6 |
| L 27-28 at | 10/16/2010 | Temple (6-4) | 10/2/2010 | L 35-42 |
| L 6-30 | 10/23/2010 | Kent State (4-6) | 11/13/2010 | W 45-28 at |
| 0-2 | 10-10 | 1-1 |
|
| 2-10 | — | 0 | (5 Common Ops) | 0 | Ball State | 4-8 |
| W 17-14 at | 10/30/2010 | Central Michigan (3-7) | 10/2/2010 | W 31-17 at |
| L 7-41 | 11/26/2010 | Western Michigan (4-6) | 10/9/2010 | L 16-45 |
| L 14-33 at | 11/17/2010 | Toledo (6-5) | 10/23/2010 | L 24-31 at |
| L 6-30 | 10/23/2010 | Kent State (3-7) | 10/30/2010 | L 14-33 at |
| L 26-28 | 10/2/2010 | Buffalo (1-9) | 11/12/2010 | W 20-3 at |
| 1-4 | 17-34 | 2-3 |
|
| 2-10 | — | 0 | (1 Common Ops) | 0 | Baylor | 7-6 |
| L 26-28 | 10/2/2010 | Buffalo (1-9) | 9/11/2010 | W 34-6 |
|
| 2-10 | — | 0 | (1 Common Ops) | 0 | Boise State | 12-1 |
| L 14-33 at | 11/17/2010 | Toledo (7-4) | 10/9/2010 | W 57-14 |
|
| 2-10 | — | 0 | (1 Common Ops) | 0 | Boston College | 7-6 |
| L 6-30 | 10/23/2010 | Kent State (4-6) | 9/11/2010 | W 26-13 |
|
| 2-9 | — | 0 | (3 Common Ops) | 1 | Buffalo | 1-10 |
| L 27-28 at | 10/16/2010 | Temple (6-4) | 10/23/2010 | L 0-42 |
| L 21-24 | 11/10/2010 | Miami-Ohio (8-4) | 10/30/2010 | L 9-21 |
| L 25-49 at | 10/9/2010 | Ohio (6-5) | 11/4/2010 | L 17-34 at |
| 0-3 | 20-13 | 0-3 |
|
| 2-10 | — | 0 | (1 Common Ops) | 0 | Central Arkansas | 0-1 |
| L 20-33 at | 9/11/2010 | Tulsa (8-3) | 9/25/2010 | L 14-41 at |
|
| 1-10 | — | 1 | (4 Common Ops) | 0 | Central Michigan | 3-8 |
| L 27-28 at | 10/16/2010 | Temple (6-4) | 9/9/2010 | L 10-13 1 at |
| L 21-24 | 11/10/2010 | Miami-Ohio (8-4) | 10/16/2010 | L 20-27 |
| L 7-41 | 11/26/2010 | Western Michigan (5-5) | 11/5/2010 | W 26-22 |
| L 14-33 at | 11/17/2010 | Toledo (6-5) | 11/26/2010 | L 31-42 at |
| 0-4 | 25-18 | 1-3 |
|
| 2-10 | — | 0 | (1 Common Ops) | 0 | Cincinnati | 4-8 |
| L 21-24 | 11/10/2010 | Miami-Ohio (9-3) | 10/9/2010 | W 45-3 |
|
| 2-10 | — | 0 | (1 Common Ops) | 0 | Colorado State | 3-9 |
| L 21-24 | 11/10/2010 | Miami-Ohio (8-4) | 9/18/2010 | L 10-31 at |
|
| 2-10 | — | 0 | (3 Common Ops) | 0 | Connecticut | 8-5 |
| L 21-65 at | 9/25/2010 | Michigan (5-6) | 9/4/2010 | L 10-30 at |
| L 27-28 at | 10/16/2010 | Temple (6-4) | 9/18/2010 | L 16-30 at |
| L 26-28 | 10/2/2010 | Buffalo (1-9) | 9/25/2010 | W 45-21 |
| 0-3 | 12-19 | 1-2 |
|
| 2-10 | — | 0 | (2 Common Ops) | 0 | East Carolina | 6-7 |
| L 20-33 at | 9/11/2010 | Tulsa (9-2) | 9/5/2010 | W 51-49 |
| W 44-28 | 9/18/2010 | Marshall (5-5) | 10/23/2010 | W 37-10 |
| 1-1 | 14-7 | 2-0 |
|
| 2-10 | — | 0 | (6 Common Ops) | 0 | Eastern Michigan | 2-10 |
| L 21-24 | 11/10/2010 | Miami-Ohio (8-4) | 9/11/2010 | L 21-28 at |
| W 17-14 at | 10/30/2010 | Central Michigan (2-8) | 9/18/2010 | L 14-52 |
| L 25-49 at | 10/9/2010 | Ohio (6-5) | 10/2/2010 | L 17-30 |
| L 14-33 at | 11/17/2010 | Toledo (6-5) | 10/30/2010 | L 7-42 |
| L 7-41 | 11/26/2010 | Western Michigan (4-6) | 11/13/2010 | L 30-45 at |
| L 26-28 | 10/2/2010 | Buffalo (1-9) | 11/20/2010 | W 21-17 at |
| 1-5 | 27-37 | 1-5 |
|
| 2-10 | — | 0 | (1 Common Ops) | 0 | Florida | 8-5 |
| L 21-24 | 11/10/2010 | Miami-Ohio (9-3) | 9/4/2010 | W 34-12 |
|
| 2-10 | — | 0 | (1 Common Ops) | 0 | Florida Atlantic | 4-8 |
| L 27-30 at | 9/4/2010 | Troy (6-5) | 12/4/2010 | L 7-44 |
|
| 2-10 | — | 0 | (2 Common Ops) | 0 | Florida Intl | 7-6 |
| L 27-30 at | 9/4/2010 | Troy (7-4) | 11/13/2010 | W 52-35 at |
| L 14-33 at | 11/17/2010 | Toledo (7-4) | 12/26/2010 | W 34-32 vs |
| 0-2 | 14-8 | 2-0 |
|
| 2-10 | — | 0 | (1 Common Ops) | 0 | Hampton | 0-1 |
| W 17-14 at | 10/30/2010 | Central Michigan (2-8) | 9/2/2010 | L 0-33 at |
|
| 2-10 | — | 0 | (1 Common Ops) | 0 | Hawaii | 10-4 |
| L 20-33 at | 9/11/2010 | Tulsa (8-3) | 12/24/2010 | L 35-62 vs |
|
| 2-10 | — | 0 | (1 Common Ops) | 0 | Houston | 5-7 |
| L 20-33 at | 9/11/2010 | Tulsa (8-3) | 11/13/2010 | L 25-28 |
|
| 2-10 | — | 0 | (1 Common Ops) | 0 | Idaho | 6-7 |
| L 7-41 | 11/26/2010 | Western Michigan (5-5) | 10/2/2010 | W 33-13 at |
|
| 2-10 | — | 0 | (1 Common Ops) | 0 | Illinois | 7-6 |
| L 21-65 at | 9/25/2010 | Michigan (5-6) | 11/6/2010 | L 65-67 3 at |
|
| 2-10 | — | 0 | (1 Common Ops) | 0 | Indiana | 5-7 |
| L 21-65 at | 9/25/2010 | Michigan (5-6) | 10/2/2010 | L 35-42 |
|
| 2-10 | — | 0 | (1 Common Ops) | 0 | Iowa | 8-5 |
| L 21-65 at | 9/25/2010 | Michigan (6-5) | 10/16/2010 | W 38-28 at |
|
| 2-9 | — | 0 | (5 Common Ops) | 1 | Kent State | 4-7 |
| L 21-24 | 11/10/2010 | Miami-Ohio (8-4) | 10/2/2010 | L 21-27 at |
| L 14-33 at | 11/17/2010 | Toledo (6-5) | 10/16/2010 | L 21-34 at |
| L 27-28 at | 10/16/2010 | Temple (6-4) | 11/6/2010 | L 10-28 |
| L 7-41 | 11/26/2010 | Western Michigan (4-6) | 11/20/2010 | L 3-38 at |
| L 25-49 at | 10/9/2010 | Ohio (7-4) | 11/26/2010 | W 28-6 |
| 0-5 | 31-23 | 1-4 |
|
| 1-10 | — | 1 | (1 Common Ops) | 0 | Marshall | 5-6 |
| L 25-49 at | 10/9/2010 | Ohio (7-4) | 9/25/2010 | W 24-23 |
|
| 2-10 | — | 0 | (1 Common Ops) | 0 | Massachusetts | 0-1 |
| L 21-65 at | 9/25/2010 | Michigan (5-6) | 9/18/2010 | L 37-42 at |
|
| 2-10 | — | 0 | (2 Common Ops) | 0 | Memphis | 1-11 |
| L 20-33 at | 9/11/2010 | Tulsa (8-3) | 10/2/2010 | L 7-48 |
| W 44-28 | 9/18/2010 | Marshall (4-6) | 11/13/2010 | L 13-28 at |
| 1-1 | 12-9 | 0-2 |
|
| 2-9 | — | 0 | (5 Common Ops) | 1 | Miami-Ohio | 9-4 |
| L 6-30 | 10/23/2010 | Kent State (4-6) | 10/2/2010 | W 27-21 |
| W 17-14 at | 10/30/2010 | Central Michigan (3-7) | 10/16/2010 | W 27-20 at |
| L 25-49 at | 10/9/2010 | Ohio (6-5) | 10/23/2010 | L 13-34 |
| L 26-28 | 10/2/2010 | Buffalo (1-9) | 10/30/2010 | W 21-9 at |
| L 27-28 at | 10/16/2010 | Temple (7-3) | 11/23/2010 | W 23-3 |
| 1-4 | 21-30 | 4-1 |
|
| 2-10 | — | 0 | (2 Common Ops) | 0 | Michigan State | 11-2 |
| L 7-41 | 11/26/2010 | Western Michigan (5-5) | 9/4/2010 | W 38-14 |
| L 21-65 at | 9/25/2010 | Michigan (6-5) | 10/9/2010 | W 34-17 at |
| 0-2 | 11-10 | 2-0 |
|
| 2-10 | — | 0 | (2 Common Ops) | 0 | Middle Tenn State | 6-7 |
| L 27-30 at | 9/4/2010 | Troy (6-5) | 10/5/2010 | L 13-42 |
| L 21-24 | 11/10/2010 | Miami-Ohio (8-4) | 1/6/2011 | L 21-35 vs |
| 0-2 | 14-9 | 0-2 |
|
| 2-10 | — | 0 | (1 Common Ops) | 0 | Mississippi State | 9-4 |
| L 21-65 at | 9/25/2010 | Michigan (6-5) | 1/1/2011 | W 52-14 vs |
|
| 2-10 | — | 0 | (1 Common Ops) | 0 | Missouri | 10-3 |
| L 21-24 | 11/10/2010 | Miami-Ohio (9-3) | 9/25/2010 | W 51-13 |
|
| 2-10 | — | 0 | (1 Common Ops) | 0 | Murray State | 0-1 |
| L 6-30 | 10/23/2010 | Kent State (3-7) | 9/2/2010 | L 10-41 at |
|
| 2-10 | — | 0 | (1 Common Ops) | 0 | Navy | 9-4 |
| W 17-14 at | 10/30/2010 | Central Michigan (3-7) | 11/13/2010 | W 38-37 |
|
| 2-10 | — | 0 | (1 Common Ops) | 0 | Nicholls State | 0-2 |
| L 7-41 | 11/26/2010 | Western Michigan (4-6) | 9/11/2010 | L 14-49 at |
|
| 2-10 | — | 0 | (1 Common Ops) | 0 | North Texas | 3-9 |
| L 27-30 at | 9/4/2010 | Troy (6-5) | 11/6/2010 | L 35-41 |
|
| 2-10 | — | 0 | (6 Common Ops) | 0 | Northern Illinois | 11-3 |
| L 27-28 at | 10/16/2010 | Temple (7-3) | 10/9/2010 | W 31-17 |
| L 26-28 | 10/2/2010 | Buffalo (1-9) | 10/16/2010 | W 45-14 |
| W 17-14 at | 10/30/2010 | Central Michigan (3-7) | 10/23/2010 | W 33-7 |
| L 7-41 | 11/26/2010 | Western Michigan (5-5) | 10/30/2010 | W 28-21 at |
| L 14-33 at | 11/17/2010 | Toledo (7-4) | 11/9/2010 | W 65-30 |
| L 21-24 | 11/10/2010 | Miami-Ohio (8-4) | 12/3/2010 | L 21-26 vs |
| 1-5 | 31-32 | 5-1 |
|
| 2-10 | — | 0 | (1 Common Ops) | 0 | Northwestern | 7-6 |
| W 17-14 at | 10/30/2010 | Central Michigan (3-7) | 9/25/2010 | W 30-25 |
|
| 2-10 | — | 0 | (3 Common Ops) | 0 | Notre Dame | 8-5 |
| L 21-65 at | 9/25/2010 | Michigan (5-6) | 9/11/2010 | L 24-28 |
| L 7-41 | 11/26/2010 | Western Michigan (5-5) | 10/16/2010 | W 44-20 |
| L 20-33 at | 9/11/2010 | Tulsa (8-3) | 10/30/2010 | L 27-28 |
| 0-3 | 18-14 | 1-2 |
|
| 2-9 | — | 0 | (7 Common Ops) | 1 | Ohio | 7-5 |
| L 14-33 at | 11/17/2010 | Toledo (6-5) | 9/11/2010 | L 13-20 |
| W 44-28 | 9/18/2010 | Marshall (4-6) | 9/25/2010 | L 23-24 at |
| L 21-24 | 11/10/2010 | Miami-Ohio (9-3) | 10/23/2010 | W 34-13 at |
| L 26-28 | 10/2/2010 | Buffalo (1-9) | 11/4/2010 | W 34-17 |
| L 27-28 at | 10/16/2010 | Temple (7-3) | 11/16/2010 | W 31-23 at |
| L 6-30 | 10/23/2010 | Kent State (3-7) | 11/26/2010 | L 6-28 at |
| L 27-30 at | 9/4/2010 | Troy (6-5) | 12/18/2010 | L 21-48 vs |
| 1-6 | 36-38 | 3-4 |
|
| 2-10 | — | 0 | (3 Common Ops) | 0 | Ohio State | 12-1 |
| W 44-28 | 9/18/2010 | Marshall (5-5) | 9/2/2010 | W 45-7 |
| L 25-49 at | 10/9/2010 | Ohio (7-4) | 9/18/2010 | W 43-7 |
| L 21-65 at | 9/25/2010 | Michigan (6-5) | 11/27/2010 | W 37-7 |
| 1-2 | 18-14 | 3-0 |
|
| 2-10 | — | 0 | (2 Common Ops) | 0 | Oklahoma State | 11-2 |
| L 27-30 at | 9/4/2010 | Troy (7-4) | 9/11/2010 | W 41-38 |
| L 20-33 at | 9/11/2010 | Tulsa (9-2) | 9/18/2010 | W 65-28 |
| 0-2 | 16-6 | 2-0 |
|
| 2-10 | — | 0 | (3 Common Ops) | 0 | Penn State | 7-6 |
| L 6-30 | 10/23/2010 | Kent State (4-6) | 9/18/2010 | W 24-0 |
| L 27-28 at | 10/16/2010 | Temple (7-3) | 9/25/2010 | W 22-13 |
| L 21-65 at | 9/25/2010 | Michigan (6-5) | 10/30/2010 | W 41-31 |
| 0-3 | 17-14 | 3-0 |
|
| 2-10 | — | 0 | (2 Common Ops) | 0 | Purdue | 4-8 |
| L 14-33 at | 11/17/2010 | Toledo (6-5) | 9/25/2010 | L 20-31 |
| L 21-65 at | 9/25/2010 | Michigan (5-6) | 11/13/2010 | L 16-27 |
| 0-2 | 11-11 | 0-2 |
|
| 2-10 | — | 0 | (1 Common Ops) | 0 | Rhode Island | 0-1 |
| L 26-28 | 10/2/2010 | Buffalo (0-10) | 9/2/2010 | L 0-31 at |
|
| 2-10 | — | 0 | (1 Common Ops) | 0 | Rice | 4-8 |
| L 20-33 at | 9/11/2010 | Tulsa (8-3) | 11/6/2010 | L 27-64 at |
|
| 2-10 | — | 0 | (2 Common Ops) | 0 | SMU | 7-7 |
| L 20-33 at | 9/11/2010 | Tulsa (9-2) | 10/9/2010 | W 21-18 |
| W 44-28 | 9/18/2010 | Marshall (5-5) | 11/20/2010 | W 31-17 |
| 1-1 | 14-7 | 2-0 |
|
| 2-10 | — | 0 | (1 Common Ops) | 0 | South Carolina | 9-5 |
| L 27-30 at | 9/4/2010 | Troy (7-4) | 11/20/2010 | W 69-24 |
|
| 2-10 | — | 0 | (2 Common Ops) | 0 | Southern Miss | 8-5 |
| W 44-28 | 9/18/2010 | Marshall (5-5) | 10/2/2010 | W 41-16 |
| L 20-33 at | 9/11/2010 | Tulsa (8-3) | 11/26/2010 | L 50-56 at |
| 1-1 | 13-8 | 1-1 |
|
| 2-9 | — | 0 | (5 Common Ops) | 1 | Temple | 7-4 |
| W 17-14 at | 10/30/2010 | Central Michigan (3-7) | 9/9/2010 | W 13-10 1 |
| L 26-28 | 10/2/2010 | Buffalo (1-9) | 10/23/2010 | W 42-0 at |
| L 6-30 | 10/23/2010 | Kent State (4-6) | 11/6/2010 | W 28-10 at |
| L 25-49 at | 10/9/2010 | Ohio (6-5) | 11/16/2010 | L 23-31 |
| L 21-24 | 11/10/2010 | Miami-Ohio (8-4) | 11/23/2010 | L 3-23 at |
| 1-4 | 22-31 | 3-2 |
|
| 2-9 | — | 0 | (4 Common Ops) | 1 | Toledo | 7-5 |
| L 25-49 at | 10/9/2010 | Ohio (7-4) | 9/11/2010 | W 20-13 at |
| L 7-41 | 11/26/2010 | Western Michigan (5-5) | 9/18/2010 | W 37-24 at |
| L 6-30 | 10/23/2010 | Kent State (4-6) | 10/16/2010 | W 34-21 |
| W 17-14 at | 10/30/2010 | Central Michigan (3-7) | 11/26/2010 | W 42-31 |
| 1-3 | 19-22 | 4-0 |
|
| 2-9 | — | 0 | (1 Common Ops) | 1 | Troy | 7-5 |
| L 25-49 at | 10/9/2010 | Ohio (7-4) | 12/18/2010 | W 48-21 vs |
|
| 2-10 | — | 0 | (2 Common Ops) | 0 | Tulane | 4-8 |
| L 20-33 at | 9/11/2010 | Tulsa (8-3) | 10/16/2010 | L 24-52 at |
| W 44-28 | 9/18/2010 | Marshall (4-6) | 11/27/2010 | L 23-38 at |
| 1-1 | 12-9 | 0-2 |
|
| 2-10 | — | 0 | (2 Common Ops) | 0 | UAB | 4-8 |
| L 27-30 at | 9/4/2010 | Troy (7-4) | 9/18/2010 | W 34-33 |
| W 44-28 | 9/18/2010 | Marshall (4-6) | 11/6/2010 | L 17-31 |
| 1-1 | 11-10 | 1-1 |
|
| 2-10 | — | 0 | (2 Common Ops) | 0 | UCF | 11-3 |
| L 26-28 | 10/2/2010 | Buffalo (1-9) | 9/18/2010 | W 24-10 at |
| W 44-28 | 9/18/2010 | Marshall (5-5) | 10/13/2010 | W 35-14 at |
| 1-1 | 6-14 | 2-0 |
|
| 2-10 | — | 0 | (2 Common Ops) | 0 | UL Lafayette | 3-9 |
| L 27-30 at | 9/4/2010 | Troy (6-5) | 10/16/2010 | L 24-31 at |
| L 25-49 at | 10/9/2010 | Ohio (6-5) | 10/30/2010 | L 31-38 at |
| 0-2 | 12-10 | 0-2 |
|
| 2-10 | — | 0 | (1 Common Ops) | 0 | UL Monroe | 5-7 |
| L 27-30 at | 9/4/2010 | Troy (7-4) | 10/30/2010 | W 28-14 |
|
| 2-10 | — | 0 | (2 Common Ops) | 0 | UTEP | 6-7 |
| L 20-33 at | 9/11/2010 | Tulsa (8-3) | 11/20/2010 | L 28-31 at |
| W 44-28 | 9/18/2010 | Marshall (4-6) | 10/30/2010 | L 12-16 at |
| 1-1 | 12-9 | 0-2 |
|
| 2-10 | — | 0 | (1 Common Ops) | 0 | Villanova | 0-1 |
| L 27-28 at | 10/16/2010 | Temple (6-4) | 9/3/2010 | L 24-31 at |
|
| 2-10 | — | 0 | (1 Common Ops) | 0 | Virginia Tech | 11-3 |
| W 17-14 at | 10/30/2010 | Central Michigan (3-7) | 10/9/2010 | W 45-21 |
|
| 2-10 | — | 0 | (1 Common Ops) | 0 | West Virginia | 9-4 |
| W 44-28 | 9/18/2010 | Marshall (5-5) | 9/10/2010 | W 24-21 1 at |
|
| 2-10 | — | 0 | (1 Common Ops) | 0 | Western Kentucky | 2-10 |
| L 27-30 at | 9/4/2010 | Troy (6-5) | 11/27/2010 | L 14-28 at |
|
| 2-9 | — | 0 | (3 Common Ops) | 1 | Western Michigan | 5-6 |
| L 14-33 at | 11/17/2010 | Toledo (6-5) | 9/18/2010 | L 24-37 |
| W 17-14 at | 10/30/2010 | Central Michigan (2-8) | 11/5/2010 | L 22-26 at |
| L 6-30 | 10/23/2010 | Kent State (4-6) | 11/20/2010 | W 38-3 |
| 1-2 | 12-19 | 1-2 |
|
| 2-10 | — | 0 | (1 Common Ops) | 0 | Wisconsin | 11-2 |
| L 21-65 at | 9/25/2010 | Michigan (6-5) | 11/20/2010 | W 48-28 at |
|
| 2-10 | — | 0 | (1 Common Ops) | 0 | Wofford | 0-1 |
| L 25-49 at | 10/9/2010 | Ohio (6-5) | 9/4/2010 | L 10-33 at |
|
| 2-10 | — | 0 | (1 Common Ops) | 0 | Wyoming | 3-9 |
| L 14-33 at | 11/17/2010 | Toledo (7-4) | 10/2/2010 | W 20-15 at |
|