11 Jan 2011 5:05pm (US Central)
| 0-2 | — | 0 | (1 Common Ops) | 0 | Arkansas | 10-3 |
| L 20-21 at | 9/25/2010 | UL Monroe (4-6) | 9/11/2010 | W 31-7 vs |
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| 0-2 | — | 0 | (1 Common Ops) | 0 | Arkansas State | 4-8 |
| L 20-21 at | 9/25/2010 | UL Monroe (4-6) | 9/18/2010 | W 34-20 |
|
| 0-2 | — | 0 | (1 Common Ops) | 0 | Army | 7-6 |
| L 21-27 at | 9/2/2010 | Tulane (3-7) | 10/9/2010 | W 41-23 at |
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| 0-2 | — | 0 | (1 Common Ops) | 0 | Auburn | 14-0 |
| L 20-21 at | 9/25/2010 | UL Monroe (4-6) | 10/2/2010 | W 52-3 |
|
| 0-2 | — | 0 | (1 Common Ops) | 0 | Florida Atlantic | 4-8 |
| L 20-21 at | 9/25/2010 | UL Monroe (3-7) | 10/9/2010 | L 17-20 at |
|
| 0-2 | — | 0 | (1 Common Ops) | 0 | Florida Intl | 7-6 |
| L 20-21 at | 9/25/2010 | UL Monroe (4-6) | 11/6/2010 | W 42-35 2 |
|
| 0-2 | — | 0 | (1 Common Ops) | 0 | Houston | 5-7 |
| L 21-27 at | 9/2/2010 | Tulane (3-7) | 9/25/2010 | W 42-23 |
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| 0-2 | — | 0 | (1 Common Ops) | 0 | LSU | 11-2 |
| L 20-21 at | 9/25/2010 | UL Monroe (4-6) | 11/13/2010 | W 51-0 |
|
| 0-2 | — | 0 | (1 Common Ops) | 0 | Marshall | 5-7 |
| L 21-27 at | 9/2/2010 | Tulane (3-7) | 11/27/2010 | W 38-23 |
|
| 0-2 | — | 0 | (1 Common Ops) | 0 | Middle Tenn State | 6-7 |
| L 20-21 at | 9/25/2010 | UL Monroe (4-6) | 10/23/2010 | W 38-10 |
|
| 0-2 | — | 0 | (1 Common Ops) | 0 | Mississippi | 4-8 |
| L 21-27 at | 9/2/2010 | Tulane (3-7) | 9/11/2010 | W 27-13 at |
|
| 0-2 | — | 0 | (1 Common Ops) | 0 | North Texas | 3-9 |
| L 20-21 at | 9/25/2010 | UL Monroe (3-7) | 11/20/2010 | L 37-49 at |
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| 0-2 | — | 0 | (1 Common Ops) | 0 | Rice | 4-8 |
| L 21-27 at | 9/2/2010 | Tulane (2-8) | 11/13/2010 | L 49-54 at |
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| 0-2 | — | 0 | (1 Common Ops) | 0 | Rutgers | 4-8 |
| L 21-27 at | 9/2/2010 | Tulane (2-8) | 10/2/2010 | L 14-17 |
|
| 0-2 | — | 0 | (1 Common Ops) | 0 | SMU | 7-7 |
| L 21-27 at | 9/2/2010 | Tulane (3-7) | 10/30/2010 | W 31-17 at |
|
| 0-2 | — | 0 | (1 Common Ops) | 0 | Southern Miss | 8-5 |
| L 21-27 at | 9/2/2010 | Tulane (3-7) | 11/6/2010 | W 46-30 at |
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| 0-2 | — | 0 | (1 Common Ops) | 0 | Troy | 8-5 |
| L 20-21 at | 9/25/2010 | UL Monroe (3-7) | 10/30/2010 | L 14-28 at |
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| 0-2 | — | 0 | (1 Common Ops) | 0 | Tulsa | 10-3 |
| L 21-27 at | 9/2/2010 | Tulane (3-7) | 10/16/2010 | W 52-24 |
|
| 0-2 | — | 0 | (1 Common Ops) | 0 | UCF | 11-3 |
| L 21-27 at | 9/2/2010 | Tulane (3-7) | 11/20/2010 | W 61-14 at |
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| 0-2 | — | 0 | (1 Common Ops) | 0 | UL Lafayette | 3-9 |
| L 20-21 at | 9/25/2010 | UL Monroe (4-6) | 11/27/2010 | W 23-22 at |
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| 0-2 | — | 0 | (1 Common Ops) | 0 | UTEP | 6-7 |
| L 21-27 at | 9/2/2010 | Tulane (2-8) | 10/23/2010 | L 24-34 |
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| 0-2 | — | 0 | (1 Common Ops) | 0 | Western Kentucky | 2-10 |
| L 20-21 at | 9/25/2010 | UL Monroe (3-7) | 10/16/2010 | L 30-35 |
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