| 8-5 | — | 0 | (3 Common Ops) | 0 | Alabama | 9-3 |
| W 24-19 at | 11/27/2010 | Duke (3-7) | 9/18/2010 | W 62-13 at |
| W 30-27 2OT vs | 12/30/2010 | Tennessee (6-5) | 10/23/2010 | W 41-10 at |
| L 24-30 vs | 9/4/2010 | LSU (9-2) | 11/6/2010 | L 21-24 at |
| 2-1 | 18-14 | 2-1 |
|
| 8-5 | — | 0 | (1 Common Ops) | 0 | Arkansas | 10-3 |
| L 24-30 vs | 9/4/2010 | LSU (10-1) | 11/27/2010 | W 31-23 vs |
|
| 8-5 | — | 0 | (2 Common Ops) | 0 | Army | 7-6 |
| W 24-19 at | 11/27/2010 | Duke (3-7) | 9/25/2010 | W 35-21 at |
| W 17-13 at | 9/25/2010 | Rutgers (3-7) | 10/16/2010 | L 20-23 1 vs |
| 2-0 | 6-14 | 1-1 |
|
| 8-5 | — | 0 | (2 Common Ops) | 0 | Auburn | 14-0 |
| W 21-16 | 10/9/2010 | Clemson (6-5) | 9/18/2010 | W 27-24 1 |
| L 24-30 vs | 9/4/2010 | LSU (10-1) | 10/23/2010 | W 24-17 |
| 1-1 | 16-6 | 2-0 |
|
| 8-5 | — | 0 | (1 Common Ops) | 0 | Boise State | 12-1 |
| L 10-26 | 11/13/2010 | Virginia Tech (10-2) | 9/6/2010 | W 33-30 vs |
|
| 8-5 | — | 0 | (6 Common Ops) | 0 | Boston College | 7-6 |
| L 10-26 | 11/13/2010 | Virginia Tech (9-3) | 9/25/2010 | L 0-19 |
| L 25-29 | 11/20/2010 | North Carolina State (7-4) | 10/9/2010 | L 17-44 at |
| W 37-35 at | 11/6/2010 | Florida State (9-3) | 10/16/2010 | L 19-24 at |
| W 21-16 | 10/9/2010 | Clemson (6-5) | 10/30/2010 | W 16-10 |
| W 24-19 at | 11/27/2010 | Duke (3-7) | 11/13/2010 | W 21-16 at |
| W 44-10 at | 10/16/2010 | Virginia (4-6) | 11/20/2010 | W 17-13 |
| 4-2 | 38-28 | 3-3 |
|
| 8-5 | — | 0 | (1 Common Ops) | 0 | BYU | 7-6 |
| W 37-35 at | 11/6/2010 | Florida State (9-3) | 9/18/2010 | L 10-34 at |
|
| 8-5 | — | 0 | (1 Common Ops) | 0 | Central Michigan | 3-9 |
| L 10-26 | 11/13/2010 | Virginia Tech (9-3) | 10/9/2010 | L 21-45 at |
|
| 8-5 | — | 0 | (2 Common Ops) | 0 | Cincinnati | 4-8 |
| L 25-29 | 11/20/2010 | North Carolina State (7-4) | 9/16/2010 | L 19-30 at |
| W 17-13 at | 9/25/2010 | Rutgers (4-6) | 11/20/2010 | W 69-38 |
| 1-1 | 11-10 | 1-1 |
|
| 7-5 | — | 1 | (4 Common Ops) | 0 | Clemson | 6-6 |
| L 10-33 at | 10/23/2010 | Miami-Florida (5-6) | 10/2/2010 | L 21-30 |
| L 24-30 | 9/18/2010 | Georgia Tech (5-6) | 10/23/2010 | W 27-13 |
| L 25-29 | 11/20/2010 | North Carolina State (8-3) | 11/6/2010 | W 14-13 |
| W 37-35 at | 11/6/2010 | Florida State (9-3) | 11/13/2010 | L 13-16 at |
| 1-3 | 27-18 | 2-2 |
|
| 8-5 | — | 0 | (1 Common Ops) | 0 | Connecticut | 8-5 |
| W 17-13 at | 9/25/2010 | Rutgers (3-7) | 10/8/2010 | L 24-27 at |
|
| 7-5 | — | 1 | (4 Common Ops) | 0 | Duke | 3-8 |
| L 10-33 at | 10/23/2010 | Miami-Florida (5-6) | 10/16/2010 | L 13-28 |
| L 10-26 | 11/13/2010 | Virginia Tech (9-3) | 10/23/2010 | L 7-44 at |
| W 44-10 at | 10/16/2010 | Virginia (4-6) | 11/6/2010 | W 56-48 |
| L 24-30 | 9/18/2010 | Georgia Tech (4-7) | 11/20/2010 | L 20-30 at |
| 1-3 | 22-22 | 1-3 |
|
| 7-5 | — | 1 | (2 Common Ops) | 0 | East Carolina | 6-6 |
| L 10-26 | 11/13/2010 | Virginia Tech (9-3) | 9/18/2010 | L 27-49 at |
| L 25-29 | 11/20/2010 | North Carolina State (8-3) | 10/16/2010 | W 33-27 1 |
| 0-2 | 17-6 | 1-1 |
|
| 8-5 | — | 0 | (1 Common Ops) | 0 | Eastern Michigan | 2-10 |
| W 44-10 at | 10/16/2010 | Virginia (3-7) | 10/23/2010 | L 21-48 at |
|
| 8-5 | — | 0 | (1 Common Ops) | 0 | Elon | 0-1 |
| W 24-19 at | 11/27/2010 | Duke (2-8) | 9/4/2010 | L 27-41 at |
|
| 8-5 | — | 0 | (3 Common Ops) | 0 | Florida | 8-5 |
| W 30-27 2OT vs | 12/30/2010 | Tennessee (6-5) | 9/18/2010 | W 31-17 at |
| L 24-30 vs | 9/4/2010 | LSU (9-2) | 10/9/2010 | L 29-33 |
| W 37-35 at | 11/6/2010 | Florida State (9-3) | 11/27/2010 | L 7-31 at |
| 2-1 | 24-10 | 1-2 |
|
| 8-5 | — | 0 | (1 Common Ops) | 0 | Florida A&M | 0-1 |
| L 10-33 at | 10/23/2010 | Miami-Florida (5-6) | 9/2/2010 | L 0-45 at |
|
| 8-5 | — | 0 | (1 Common Ops) | 0 | Florida Intl | 7-6 |
| W 17-13 at | 9/25/2010 | Rutgers (3-7) | 9/11/2010 | L 14-19 |
|
| 7-5 | — | 1 | (5 Common Ops) | 0 | Florida State | 10-3 |
| W 44-10 at | 10/16/2010 | Virginia (4-6) | 10/2/2010 | W 34-14 at |
| L 10-33 at | 10/23/2010 | Miami-Florida (6-5) | 10/9/2010 | W 45-17 at |
| L 25-29 | 11/20/2010 | North Carolina State (7-4) | 10/28/2010 | L 24-28 at |
| W 21-16 | 10/9/2010 | Clemson (6-5) | 11/13/2010 | W 16-13 |
| L 10-26 | 11/13/2010 | Virginia Tech (9-3) | 12/4/2010 | L 33-44 vs |
| 2-3 | 32-23 | 3-2 |
|
| 8-5 | — | 0 | (2 Common Ops) | 0 | Georgia | 6-7 |
| W 30-27 2OT vs | 12/30/2010 | Tennessee (6-5) | 10/9/2010 | W 41-14 |
| L 24-30 | 9/18/2010 | Georgia Tech (5-6) | 11/27/2010 | W 42-34 |
| 1-1 | 11-11 | 2-0 |
|
| 8-4 | — | 0 | (6 Common Ops) | 1 | Georgia Tech | 5-7 |
| L 25-29 | 11/20/2010 | North Carolina State (7-4) | 9/25/2010 | L 28-45 |
| W 44-10 at | 10/16/2010 | Virginia (4-6) | 10/9/2010 | W 33-21 |
| W 21-16 | 10/9/2010 | Clemson (5-6) | 10/23/2010 | L 13-27 at |
| L 10-26 | 11/13/2010 | Virginia Tech (9-3) | 11/4/2010 | L 21-28 at |
| L 10-33 at | 10/23/2010 | Miami-Florida (5-6) | 11/13/2010 | L 10-35 |
| W 24-19 at | 11/27/2010 | Duke (3-7) | 11/20/2010 | W 30-20 |
| 3-3 | 33-32 | 2-4 |
|
| 8-5 | — | 0 | (1 Common Ops) | 0 | James Madison | 1-0 |
| L 10-26 | 11/13/2010 | Virginia Tech (10-2) | 9/11/2010 | W 21-16 at |
|
| 8-5 | — | 0 | (1 Common Ops) | 0 | Kansas | 3-9 |
| L 24-30 | 9/18/2010 | Georgia Tech (5-6) | 9/11/2010 | W 28-25 |
|
| 8-5 | — | 0 | (1 Common Ops) | 0 | Kentucky | 6-7 |
| W 30-27 2OT vs | 12/30/2010 | Tennessee (5-6) | 11/27/2010 | L 14-24 at |
|
| 8-5 | — | 0 | (1 Common Ops) | 0 | Louisville | 7-6 |
| W 17-13 at | 9/25/2010 | Rutgers (4-6) | 11/26/2010 | W 40-13 at |
|
| 8-4 | — | 0 | (1 Common Ops) | 1 | LSU | 10-2 |
| W 30-27 2OT vs | 12/30/2010 | Tennessee (6-5) | 10/2/2010 | W 16-14 |
|
| 8-5 | — | 0 | (1 Common Ops) | 0 | Marshall | 5-7 |
| W 42-17 | 10/2/2010 | East Carolina (5-6) | 10/23/2010 | L 10-37 at |
|
| 8-5 | — | 0 | (7 Common Ops) | 0 | Maryland | 9-4 |
| W 42-17 | 10/2/2010 | East Carolina (6-5) | 12/29/2010 | W 51-20 vs |
| W 21-16 | 10/9/2010 | Clemson (5-6) | 10/16/2010 | L 7-31 at |
| W 44-10 at | 10/16/2010 | Virginia (4-6) | 11/13/2010 | W 42-23 at |
| L 10-33 at | 10/23/2010 | Miami-Florida (5-6) | 11/6/2010 | L 20-26 at |
| W 37-35 at | 11/6/2010 | Florida State (9-3) | 11/20/2010 | L 16-30 |
| L 25-29 | 11/20/2010 | North Carolina State (8-3) | 11/27/2010 | W 38-31 |
| W 24-19 at | 11/27/2010 | Duke (3-7) | 10/2/2010 | W 21-16 |
| 5-2 | 40-36 | 4-3 |
|
| 8-5 | — | 0 | (1 Common Ops) | 0 | McNeese State | 0-2 |
| L 24-30 vs | 9/4/2010 | LSU (9-2) | 10/16/2010 | L 10-32 at |
|
| 8-5 | — | 0 | (2 Common Ops) | 0 | Memphis | 1-11 |
| W 42-17 | 10/2/2010 | East Carolina (5-6) | 9/11/2010 | L 27-49 at |
| W 30-27 2OT vs | 12/30/2010 | Tennessee (5-6) | 11/6/2010 | L 14-50 |
| 2-0 | 10-12 | 0-2 |
|
| 8-4 | — | 0 | (6 Common Ops) | 1 | Miami-Florida | 6-6 |
| W 21-16 | 10/9/2010 | Clemson (6-5) | 10/2/2010 | W 30-21 at |
| W 37-35 at | 11/6/2010 | Florida State (9-3) | 10/9/2010 | L 17-45 |
| W 24-19 at | 11/27/2010 | Duke (3-7) | 10/16/2010 | W 28-13 at |
| W 44-10 at | 10/16/2010 | Virginia (3-7) | 10/30/2010 | L 19-24 at |
| L 24-30 | 9/18/2010 | Georgia Tech (5-6) | 11/13/2010 | W 35-10 at |
| L 10-26 | 11/13/2010 | Virginia Tech (9-3) | 11/20/2010 | L 17-31 |
| 4-2 | 35-31 | 3-3 |
|
| 8-5 | — | 0 | (1 Common Ops) | 0 | Middle Tenn State | 6-7 |
| L 24-30 | 9/18/2010 | Georgia Tech (4-7) | 10/16/2010 | L 14-42 at |
|
| 8-5 | — | 0 | (2 Common Ops) | 0 | Mississippi | 4-8 |
| W 30-27 2OT vs | 12/30/2010 | Tennessee (5-6) | 11/13/2010 | L 14-52 at |
| L 24-30 vs | 9/4/2010 | LSU (9-2) | 11/20/2010 | L 36-43 at |
| 1-1 | 14-8 | 0-2 |
|
| 8-5 | — | 0 | (1 Common Ops) | 0 | Mississippi State | 9-4 |
| L 24-30 vs | 9/4/2010 | LSU (9-2) | 9/18/2010 | L 7-29 at |
|
| 8-5 | — | 0 | (2 Common Ops) | 0 | Navy | 9-4 |
| W 42-17 | 10/2/2010 | East Carolina (6-5) | 11/6/2010 | W 76-35 at |
| W 24-19 at | 11/27/2010 | Duke (2-8) | 10/30/2010 | L 31-34 |
| 2-0 | 8-13 | 1-1 |
|
| 8-5 | — | 0 | (1 Common Ops) | 0 | Norfolk State | 0-1 |
| W 17-13 at | 9/25/2010 | Rutgers (3-7) | 9/2/2010 | L 0-31 at |
|
| 8-4 | — | 0 | (5 Common Ops) | 1 | North Carolina State | 8-4 |
| L 24-30 | 9/18/2010 | Georgia Tech (5-6) | 9/25/2010 | W 45-28 at |
| W 42-17 | 10/2/2010 | East Carolina (5-6) | 10/16/2010 | L 27-33 1 at |
| W 21-16 | 10/9/2010 | Clemson (5-6) | 11/6/2010 | L 13-14 at |
| W 37-35 at | 11/6/2010 | Florida State (10-2) | 10/28/2010 | W 28-24 |
| L 10-26 | 11/13/2010 | Virginia Tech (9-3) | 10/2/2010 | L 30-41 |
| 3-2 | 34-23 | 2-3 |
|
| 8-5 | — | 0 | (1 Common Ops) | 0 | North Texas | 3-9 |
| W 21-16 | 10/9/2010 | Clemson (5-6) | 9/4/2010 | L 10-35 at |
|
| 8-5 | — | 0 | (1 Common Ops) | 0 | Notre Dame | 8-5 |
| L 10-33 at | 10/23/2010 | Miami-Florida (6-5) | 12/31/2010 | W 33-17 vs |
|
| 8-5 | — | 0 | (1 Common Ops) | 0 | Ohio State | 12-1 |
| L 10-33 at | 10/23/2010 | Miami-Florida (6-5) | 9/11/2010 | W 36-24 |
|
| 8-5 | — | 0 | (1 Common Ops) | 0 | Oklahoma | 12-2 |
| W 37-35 at | 11/6/2010 | Florida State (10-2) | 9/11/2010 | W 47-17 |
|
| 8-5 | — | 0 | (1 Common Ops) | 0 | Oregon | 12-1 |
| W 30-27 2OT vs | 12/30/2010 | Tennessee (6-5) | 9/11/2010 | W 48-13 at |
|
| 8-5 | — | 0 | (2 Common Ops) | 0 | Pittsburgh | 8-5 |
| L 10-33 at | 10/23/2010 | Miami-Florida (5-6) | 9/23/2010 | L 3-31 |
| W 17-13 at | 9/25/2010 | Rutgers (4-6) | 10/23/2010 | W 41-21 |
| 1-1 | 9-12 | 1-1 |
|
| 8-5 | — | 0 | (1 Common Ops) | 0 | Presbyterian | 0-2 |
| W 21-16 | 10/9/2010 | Clemson (5-6) | 9/11/2010 | L 21-58 at |
|
| 8-5 | — | 0 | (1 Common Ops) | 0 | Rice | 4-8 |
| W 42-17 | 10/2/2010 | East Carolina (6-5) | 11/20/2010 | W 62-38 |
|
| 8-5 | — | 0 | (1 Common Ops) | 0 | Richmond | 0-1 |
| W 44-10 at | 10/16/2010 | Virginia (3-7) | 9/4/2010 | L 13-34 at |
|
| 8-5 | — | 0 | (1 Common Ops) | 0 | Samford | 0-1 |
| W 37-35 at | 11/6/2010 | Florida State (9-3) | 9/4/2010 | L 6-59 at |
|
| 8-5 | — | 0 | (1 Common Ops) | 0 | SMU | 7-7 |
| W 42-17 | 10/2/2010 | East Carolina (6-5) | 11/26/2010 | W 45-38 1 at |
|
| 8-5 | — | 0 | (3 Common Ops) | 0 | South Carolina | 9-5 |
| W 30-27 2OT vs | 12/30/2010 | Tennessee (6-5) | 10/30/2010 | W 38-24 |
| W 21-16 | 10/9/2010 | Clemson (6-5) | 11/27/2010 | W 29-7 at |
| W 37-35 at | 11/6/2010 | Florida State (9-3) | 12/31/2010 | L 17-26 vs |
| 3-0 | 21-13 | 2-1 |
|
| 8-5 | — | 0 | (1 Common Ops) | 0 | South Carolina State | 0-1 |
| L 24-30 | 9/18/2010 | Georgia Tech (4-7) | 9/4/2010 | L 10-41 at |
|
| 8-5 | — | 0 | (3 Common Ops) | 0 | South Florida | 8-5 |
| W 17-13 at | 9/25/2010 | Rutgers (4-6) | 11/3/2010 | W 28-27 |
| W 21-16 | 10/9/2010 | Clemson (6-5) | 12/31/2010 | W 31-26 vs |
| L 10-33 at | 10/23/2010 | Miami-Florida (6-5) | 11/27/2010 | W 23-20 1 at |
| 2-1 | 16-16 | 3-0 |
|
| 8-5 | — | 0 | (1 Common Ops) | 0 | Southern California | 8-5 |
| W 44-10 at | 10/16/2010 | Virginia (4-6) | 9/11/2010 | W 17-7 |
|
| 8-5 | — | 0 | (1 Common Ops) | 0 | Southern Miss | 8-5 |
| W 42-17 | 10/2/2010 | East Carolina (5-6) | 10/9/2010 | L 43-44 |
|
| 8-5 | — | 0 | (1 Common Ops) | 0 | Stanford | 12-1 |
| L 10-26 | 11/13/2010 | Virginia Tech (10-2) | 1/3/2011 | W 40-12 vs |
|
| 8-5 | — | 0 | (1 Common Ops) | 0 | Syracuse | 8-5 |
| W 17-13 at | 9/25/2010 | Rutgers (4-6) | 11/13/2010 | W 13-10 at |
|
| 7-5 | — | 1 | (1 Common Ops) | 0 | Tennessee | 6-6 |
| L 24-30 vs | 9/4/2010 | LSU (9-2) | 10/2/2010 | L 14-16 at |
|
| 8-5 | — | 0 | (1 Common Ops) | 0 | Tennessee-Martin | 0-1 |
| W 30-27 2OT vs | 12/30/2010 | Tennessee (5-6) | 9/4/2010 | L 0-50 at |
|
| 8-5 | — | 0 | (1 Common Ops) | 0 | Texas A&M | 9-4 |
| L 24-30 vs | 9/4/2010 | LSU (9-2) | 1/7/2011 | L 24-41 vs |
|
| 8-5 | — | 0 | (1 Common Ops) | 0 | Tulane | 4-8 |
| W 17-13 at | 9/25/2010 | Rutgers (4-6) | 10/2/2010 | W 17-14 at |
|
| 8-5 | — | 0 | (1 Common Ops) | 0 | Tulsa | 10-3 |
| W 42-17 | 10/2/2010 | East Carolina (5-6) | 9/5/2010 | L 49-51 at |
|
| 8-5 | — | 0 | (2 Common Ops) | 0 | UAB | 4-8 |
| W 30-27 2OT vs | 12/30/2010 | Tennessee (5-6) | 9/25/2010 | L 29-32 2 at |
| W 42-17 | 10/2/2010 | East Carolina (5-6) | 11/11/2010 | L 42-54 |
| 2-0 | 10-12 | 0-2 |
|
| 8-5 | — | 0 | (2 Common Ops) | 0 | UCF | 11-3 |
| L 25-29 | 11/20/2010 | North Carolina State (7-4) | 9/11/2010 | L 21-28 |
| W 42-17 | 10/2/2010 | East Carolina (6-5) | 10/30/2010 | W 49-35 |
| 1-1 | 13-9 | 1-1 |
|
| 8-5 | — | 0 | (1 Common Ops) | 0 | UL Monroe | 5-7 |
| L 24-30 vs | 9/4/2010 | LSU (9-2) | 11/13/2010 | L 0-51 at |
|
| 8-5 | — | 0 | (2 Common Ops) | 0 | Vanderbilt | 2-10 |
| L 24-30 vs | 9/4/2010 | LSU (9-2) | 9/11/2010 | L 3-27 |
| W 30-27 2OT vs | 12/30/2010 | Tennessee (5-6) | 11/20/2010 | L 10-24 |
| 1-1 | 14-8 | 0-2 |
|
| 7-5 | — | 1 | (5 Common Ops) | 0 | Virginia | 4-7 |
| L 24-30 | 9/18/2010 | Georgia Tech (4-7) | 10/9/2010 | L 21-33 at |
| L 10-33 at | 10/23/2010 | Miami-Florida (6-5) | 10/30/2010 | W 24-19 |
| W 37-35 at | 11/6/2010 | Florida State (9-3) | 10/2/2010 | L 14-34 |
| L 10-26 | 11/13/2010 | Virginia Tech (9-3) | 11/27/2010 | L 7-37 at |
| W 24-19 at | 11/27/2010 | Duke (2-8) | 11/6/2010 | L 48-56 at |
| 2-3 | 30-26 | 1-4 |
|
| 8-4 | — | 0 | (7 Common Ops) | 1 | Virginia Tech | 10-3 |
| L 24-30 | 9/18/2010 | Georgia Tech (5-6) | 11/4/2010 | W 28-21 |
| W 42-17 | 10/2/2010 | East Carolina (6-5) | 9/18/2010 | W 49-27 |
| W 44-10 at | 10/16/2010 | Virginia (4-6) | 11/27/2010 | W 37-7 |
| L 10-33 at | 10/23/2010 | Miami-Florida (6-5) | 11/20/2010 | W 31-17 at |
| W 37-35 at | 11/6/2010 | Florida State (10-2) | 12/4/2010 | W 44-33 vs |
| L 25-29 | 11/20/2010 | North Carolina State (8-3) | 10/2/2010 | W 41-30 at |
| W 24-19 at | 11/27/2010 | Duke (3-7) | 10/23/2010 | W 44-7 |
| 4-3 | 42-34 | 7-0 |
|
| 8-5 | — | 0 | (1 Common Ops) | 0 | VMI | 0-2 |
| W 44-10 at | 10/16/2010 | Virginia (3-7) | 9/25/2010 | L 7-48 at |
|
| 8-5 | — | 0 | (6 Common Ops) | 0 | Wake Forest | 3-9 |
| W 24-19 at | 11/27/2010 | Duke (3-7) | 9/11/2010 | W 54-48 |
| W 37-35 at | 11/6/2010 | Florida State (9-3) | 9/25/2010 | L 0-31 at |
| L 24-30 | 9/18/2010 | Georgia Tech (4-7) | 10/2/2010 | L 20-24 |
| L 10-26 | 11/13/2010 | Virginia Tech (9-3) | 10/16/2010 | L 21-52 at |
| L 25-29 | 11/20/2010 | North Carolina State (7-4) | 11/13/2010 | L 3-38 at |
| W 21-16 | 10/9/2010 | Clemson (5-6) | 11/20/2010 | L 10-30 |
| 3-3 | 37-30 | 1-5 |
|
| 8-5 | — | 0 | (3 Common Ops) | 0 | West Virginia | 9-4 |
| L 24-30 vs | 9/4/2010 | LSU (9-2) | 9/25/2010 | L 14-20 at |
| W 17-13 at | 9/25/2010 | Rutgers (4-6) | 12/4/2010 | W 35-14 |
| L 25-29 | 11/20/2010 | North Carolina State (7-4) | 12/28/2010 | L 7-23 vs |
| 1-2 | 20-12 | 1-2 |
|
| 8-5 | — | 0 | (1 Common Ops) | 0 | Western Carolina | 0-1 |
| L 25-29 | 11/20/2010 | North Carolina State (7-4) | 9/4/2010 | L 7-48 at |
|