| 9/4/2010 | Geneva 32 @ Frostburg State Bobcats 27 | |
| 9/11/2010 | Albright Lions 54 @ Geneva 27 | |
| 9/18/2010 | Thomas More Saints 36 @ Geneva 20 | † |
| 9/25/2010 | Geneva 37 @ Bethany WV Bison 33 | † |
| 10/2/2010 | Geneva 27 @ St Vincent Bearcats 23 | † |
| 10/9/2010 | Waynesburg Yellow Jackets 55 @ Geneva 42 | † |
| 10/16/2010 | Geneva 7 @ Grove City Wolverines 13 | † |
| 10/23/2010 | Washington & Jefferson Presidents 22 @ Geneva 16 | † |
| 10/30/2010 | Geneva 34 @ Thiel Tomcats 20 | † |
| 11/13/2010 | Westminster PA Titans 24 @ Geneva 30 | † |