| 8/28/2010 | Wayne State NE Warriors 24 @ Nebraska-Kearney 17 | |
| 9/4/2010 | Nebraska-Kearney 32 @ Nebraska-Omaha Mavericks 29 | |
| 9/18/2010 | Mesa State Mavericks 9 @ Nebraska-Kearney 31 | † |
| 9/25/2010 | Nebraska-Kearney 13 @ Western State Mountaineers 6 | † |
| 10/2/2010 | Adams State Grizzlies 17 @ Nebraska-Kearney 27 | † |
| 10/9/2010 | Nebraska-Kearney 35 @ Chadron State Eagles 21 | † |
| 10/16/2010 | Nebraska-Kearney 38 @ Colorado State -Pueblo ThunderWolves 24 | † |
| 10/23/2010 | New Mexico Highlands Cowboys 13 @ Nebraska-Kearney 38 | † |
| 10/30/2010 | Nebraska-Kearney 56 @ Western New Mexico Mustangs 31 | † |
| 11/6/2010 | Fort Lewis Skyhawks 21 @ Nebraska-Kearney 48 | † |
| 11/13/2010 | Nebraska-Kearney 53 @ Colorado Mines Orediggers 55 3OT | † |