| 8/28/2010 | Dixie State Rebels 14 @ Adams State 34 | |
| 9/4/2010 | Adams State 0 @ Northern Colorado Bears 54 | |
| 9/18/2010 | Adams State 10 @ Colorado State -Pueblo ThunderWolves 27 | † |
| 9/25/2010 | Chadron State Eagles 21 @ Adams State 10 | † |
| 10/2/2010 | Adams State 17 @ Nebraska-Kearney Lopers 27 | † |
| 10/9/2010 | New Mexico Highlands Cowboys 0 @ Adams State 55 | † |
| 10/16/2010 | Adams State 14 @ Western New Mexico Mustangs 10 | † |
| 10/23/2010 | Fort Lewis Skyhawks 14 @ Adams State 7 | † |
| 10/30/2010 | Adams State 17 @ Colorado Mines Orediggers 24 | † |
| 11/6/2010 | Mesa State Mavericks 34 @ Adams State 41 | † |
| 11/13/2010 | Adams State 28 @ Western State Mountaineers 19 | † |