| 9/4/2010 | Colorado State 3 vs Colorado Buffaloes 24 (Denver CO) | |
| 9/11/2010 | Colorado State 6 @ Nevada Wolf Pack 51 | |
| 9/18/2010 | Colorado State 10 @ Miami-Ohio Redhawks 31 | |
| 9/25/2010 | Idaho Vandals 34 @ Colorado State 36 | |
| 10/2/2010 | TCU Horned Frogs 27 @ Colorado State 0 | † |
| 10/9/2010 | Colorado State 27 @ Air Force Falcons 49 | † |
| 10/16/2010 | UNLV Rebels 10 @ Colorado State 43 | † |
| 10/23/2010 | Colorado State 6 @ Utah Utes 59 | † |
| 10/30/2010 | New Mexico Lobos 14 @ Colorado State 38 | † |
| 11/6/2010 | Colorado State 19 @ San Diego State Aztecs 24 | † |
| 11/13/2010 | BYU Cougars 49 @ Colorado State 10 | † |
| 11/20/2010 | Colorado State 0 @ Wyoming Cowboys 44 | † |