| 9/4/2010 | McMurry @ Bacone | |
| 9/4/2010 | Louisiana College @ Belhaven | |
| 9/4/2010 | Mississippi College @ Millsaps | |
| 9/4/2010 | Howard Payne @ Trinity TX | |
| 9/4/2010 | East Texas Baptist @ Wisconsin-La Crosse | |
| 9/4/2010 | Hardin-Simmons @ Whitworth | |
| 9/11/2010 | Texas Lutheran @ Austin | |
| 9/11/2010 | Redlands @ East Texas Baptist | |
| 9/11/2010 | Willamette @ Hardin-Simmons | |
| 9/11/2010 | Southwestern Assemblies of God @ Howard Payne | |
| 9/11/2010 | Huntingdon AL @ Louisiana College | |
| 9/11/2010 | Texas College @ McMurry | |
| 9/11/2010 | Belhaven @ Mississippi College | |
| 9/11/2010 | Western New Mexico @ Sul Ross State | |
| 9/11/2010 | Mary Hardin-Baylor @ Wisconsin-La Crosse | |
| 9/18/2010 | Mississippi College @ Hardin-Simmons | † |
| 9/18/2010 | Mary Hardin-Baylor @ McMurry | † |
| 9/18/2010 | Howard Payne @ Sul Ross State | † |
| 9/18/2010 | East Texas Baptist @ Texas Lutheran | † |
| 9/25/2010 | McMurry @ East Texas Baptist | † |
| 9/25/2010 | Texas Lutheran @ Howard Payne | † |
| 9/25/2010 | Hardin-Simmons @ Mary Hardin-Baylor | † |
| 9/25/2010 | Louisiana College @ Mississippi College | † |
| 10/2/2010 | East Texas Baptist @ Hardin-Simmons | † |
| 10/2/2010 | Mary Hardin-Baylor @ Louisiana College | † |
| 10/2/2010 | Howard Payne @ McMurry | † |
| 10/2/2010 | Sul Ross State @ Texas Lutheran | † |
| 10/9/2010 | Louisiana College @ East Texas Baptist | † |
| 10/9/2010 | Hardin-Simmons @ Howard Payne | † |
| 10/9/2010 | Mississippi College @ Mary Hardin-Baylor | † |
| 10/9/2010 | McMurry @ Sul Ross State | † |
| 10/9/2010 | Trinity TX @ Texas Lutheran | |
| 10/16/2010 | Sul Ross State @ Hardin-Simmons | † |
| 10/16/2010 | Howard Payne @ Louisiana College | † |
| 10/16/2010 | Texas Lutheran @ McMurry | † |
| 10/16/2010 | East Texas Baptist @ Mississippi College | † |
| 10/16/2010 | Mary Hardin-Baylor @ Southern Oregon | |
| 10/23/2010 | Mary Hardin-Baylor @ East Texas Baptist | † |
| 10/23/2010 | Mississippi College @ Howard Payne | † |
| 10/23/2010 | Louisiana College @ Sul Ross State | † |
| 10/23/2010 | Hardin-Simmons @ Texas Lutheran | † |
| 10/30/2010 | McMurry @ Hardin-Simmons | † |
| 10/30/2010 | Texas Lutheran @ Louisiana College | † |
| 10/30/2010 | Howard Payne @ Mary Hardin-Baylor | † |
| 10/30/2010 | Sul Ross State @ Mississippi College | † |
| 11/6/2010 | East Texas Baptist @ Howard Payne | † |
| 11/6/2010 | Louisiana College @ McMurry | † |
| 11/6/2010 | Mary Hardin-Baylor @ Sul Ross State | † |
| 11/6/2010 | Mississippi College @ Texas Lutheran | † |
| 11/13/2010 | Sul Ross State @ East Texas Baptist | † |
| 11/13/2010 | Hardin-Simmons @ Louisiana College | † |
| 11/13/2010 | Texas Lutheran @ Mary Hardin-Baylor | † |
| 11/13/2010 | McMurry @ Mississippi College | † |