| 9/4/2010 | Howard Payne Yellow Jackets 34 @ Trinity TX 40 2OT | |
| 9/18/2010 | Rhodes Lynx 22 @ Trinity TX 16 | † |
| 9/25/2010 | Millsaps Majors 27 @ Trinity TX 23 | † |
| 10/2/2010 | Trinity TX 38 @ Birmingham-Southern Panthers 28 | † |
| 10/9/2010 | Trinity TX 14 @ Texas Lutheran Bulldogs 42 | |
| 10/16/2010 | Trinity TX 17 @ Sewanee Tigers 3 | † |
| 10/23/2010 | DePauw Tigers 32 @ Trinity TX 31 | † |
| 10/30/2010 | Trinity TX 30 @ Huntingdon AL Hawks 56 | |
| 11/6/2010 | Trinity TX 7 @ Centre Praying Colonels 26 | † |
| 11/13/2010 | Austin Kangaroos 24 @ Trinity TX 28 | † |