| 9/3/2022 | Howard Payne | 59 | at | Texas Lutheran (4-6,3-5) | 45 | |||
| 9/10/2022 | George Fox (8-2) | 42 | at | Howard Payne | 39 | NWC | ||
| 9/17/2022 | Howard Payne | 67 | vs | Hendrix (3-7) | 10 | Prosper TX | vs SAA | |
| 9/24/2022 | East Texas Baptist (5-5,4-4) | 21 | at | Howard Payne | 33 | |||
| 10/1/2022 | Howard Payne | 56 | at | Sul Ross State (4-6,4-4) | 42 | |||
| 10/8/2022 | McMurry (1-9,1-7) | 18 | at | Howard Payne | 30 | |||
| 10/15/2022 | Southwestern Texas (3-7,2-6) | 17 | at | Howard Payne | 48 | |||
| 10/29/2022 | Howard Payne | 19 | at | Hardin-Simmons (9-2,7-1) | 28 | |||
| 11/5/2022 | Mary Hardin-Baylor (12-2,8-0) | 27 | at | Howard Payne | 24 | |||
| 11/12/2022 | Howard Payne | 23 | at | Austin (1-9,1-7) | 20 |
| vs Howard Payne | vs Other Opponents | Howard Payne compared to OOs | |
| Record: | 3-7 | 47-48 | |
| Points Scored: | 27.00 | 26.64 | -0.36 |
| Points Allowed: | 39.80 | 26.47 | 13.33 |
| Margin: | -12.80 | 0.17 | 12.97 |
| Total Points: | 66.80 | 53.11 | 13.69 |