| 9/3/2022 | McMurry | 9 | vs | Birmingham-Southern (7-3) | 26 | Little Rock AR | vs SAA | |
| 9/10/2022 | Millsaps (3-7) | 27 | at | McMurry | 13 | SAA | ||
| 9/17/2022 | East Texas Baptist (5-5,4-4) | 28 | at | McMurry | 7 | |||
| 9/24/2022 | McMurry | 33 | at | Southwestern Texas (3-7,2-6) | 38 | |||
| 10/1/2022 | Hardin-Simmons (9-2,7-1) | 45 | at | McMurry | 13 | |||
| 10/8/2022 | McMurry | 18 | at | Howard Payne (7-3,6-2) | 30 | |||
| 10/15/2022 | McMurry | 24 | at | Austin (1-9,1-7) | 21 | |||
| 10/22/2022 | Texas Lutheran (4-6,3-5) | 17 | at | McMurry | 10 | |||
| 10/29/2022 | McMurry | 27 | at | Sul Ross State (4-6,4-4) | 33 | |||
| 11/12/2022 | McMurry | 3 | at | Mary Hardin-Baylor (12-2,8-0) | 62 |
| vs McMurry | vs Other Opponents | McMurry compared to OOs | |
| Record: | 9-1 | 46-49 | |
| Points Scored: | 32.70 | 27.99 | -4.71 |
| Points Allowed: | 15.70 | 28.31 | -12.61 |
| Margin: | 17.00 | -0.32 | -17.32 |
| Total Points: | 48.40 | 56.30 | -7.90 |