| 9/3/2022 | Howard Payne (7-3,6-2) | 59 | at | Texas Lutheran | 45 | |||
| 9/17/2022 | Texas Lutheran | 14 | at | Trinity TX (11-1) | 52 | at SAA | ||
| 9/24/2022 | Sul Ross State (4-6,4-4) | 28 | at | Texas Lutheran | 14 | |||
| 10/1/2022 | Texas Lutheran | 45 | at | North American U (1-8) | 17 | at None | ||
| 10/8/2022 | Texas Lutheran | 37 | at | Austin (1-9,1-7) | 15 | |||
| 10/15/2022 | Mary Hardin-Baylor (12-2,8-0) | 45 | at | Texas Lutheran | 16 | |||
| 10/22/2022 | Texas Lutheran | 17 | at | McMurry (1-9,1-7) | 10 | |||
| 10/29/2022 | East Texas Baptist (5-5,4-4) | 38 | at | Texas Lutheran | 35 | |||
| 11/5/2022 | Texas Lutheran | 21 | at | Southwestern Texas (3-7,2-6) | 17 | |||
| 11/12/2022 | Hardin-Simmons (9-2,7-1) | 45 | at | Texas Lutheran | 16 |
| vs Texas Lutheran | vs Other Opponents | Texas Lutheran compared to OOs | |
| Record: | 6-4 | 48-48 | |
| Points Scored: | 32.60 | 27.31 | -5.29 |
| Points Allowed: | 26.00 | 27.75 | -1.75 |
| Margin: | 6.60 | -0.44 | -7.04 |
| Total Points: | 58.60 | 55.06 | 3.54 |