| 9/2/2022 | Alfred (2-8) | 6 | at | Hobart | 36 | E8 | ||
| 9/10/2022 | Hobart | 13 | at | Morrisville (7-4) | 24 | at E8 | ||
| 9/17/2022 | St John Fisher (4-6) | 0 | at | Hobart | 17 | E8 | ||
| 9/24/2022 | Hobart | 65 | at | Keystone (3-7) | 6 | at ECFC | ||
| 10/1/2022 | Ithaca (12-1,6-0) | 31 | at | Hobart | 7 | |||
| 10/15/2022 | Hobart | 13 | at | Rensselaer (8-3,5-1) | 16 | |||
| 10/22/2022 | Hobart | 31 | at | St Lawrence (4-6,2-4) | 10 | |||
| 10/29/2022 | Union NY (6-4,3-3) | 21 | at | Hobart | 23 | |||
| 11/5/2022 | Hobart | 63 | at | Buffalo State (0-10,0-6) | 7 | |||
| 11/12/2022 | Rochester (3-7,1-5) | 7 | at | Hobart | 27 | |||
| 11/19/2022 | Hobart | 18 | at | Washington & Jefferson (9-2) | 35 | at TPAC |
| vs Hobart | vs Other Opponents | Hobart compared to OOs | |
| Record: | 4-7 | 54-51 | |
| Points Scored: | 14.82 | 23.54 | 8.72 |
| Points Allowed: | 28.45 | 22.15 | 6.30 |
| Margin: | -13.63 | 1.39 | 15.02 |
| Total Points: | 43.27 | 45.69 | -2.42 |