| 9/3/2022 | Buffalo State | 21 | at | St John Fisher (4-6) | 62 | at E8 | ||
| 9/17/2022 | Cortland (9-2) | 66 | at | Buffalo State | 7 | E8 | ||
| 9/24/2022 | Morrisville (7-4) | 31 | at | Buffalo State | 10 | E8 | ||
| 10/1/2022 | Buffalo State | 0 | at | Union NY (6-4,3-3) | 45 | |||
| 10/8/2022 | Rensselaer (8-3,5-1) | 42 | at | Buffalo State | 14 | |||
| 10/15/2022 | Buffalo State | 6 | at | Rochester (3-7,1-5) | 12 | |||
| 10/21/2022 | Ithaca (12-1,6-0) | 51 | at | Buffalo State | 10 | |||
| 10/29/2022 | Buffalo State | 2 | at | Brockport State (7-3) | 54 | at E8 | ||
| 11/5/2022 | Hobart (7-4,4-2) | 63 | at | Buffalo State | 7 | |||
| 11/12/2022 | Buffalo State | 7 | at | St Lawrence (4-6,2-4) | 31 |
| vs Buffalo State | vs Other Opponents | Buffalo State compared to OOs | |
| Record: | 10-0 | 57-40 | |
| Points Scored: | 45.70 | 23.96 | -21.74 |
| Points Allowed: | 8.40 | 17.64 | -9.24 |
| Margin: | 37.30 | 6.32 | -30.98 |
| Total Points: | 54.10 | 41.60 | 12.50 |