| 8/27/2022 | Nebraska | 28 | vs | Northwestern (1-11,1-8) | 31 | Dublin IE | ||
| 9/3/2022 | North Dakota (7-5) | 17 | at | Nebraska | 38 | MVC (1AA) | ||
| 9/10/2022 | Georgia Southern (6-7) | 45 | at | Nebraska | 42 | SBC | ||
| 9/17/2022 | Oklahoma (6-7) | 49 | at | Nebraska | 14 | B12 | ||
| 10/1/2022 | Indiana (4-8,2-7) | 21 | at | Nebraska | 35 | |||
| 10/7/2022 | Nebraska | 14 | at | Rutgers (4-8,1-8) | 13 | |||
| 10/15/2022 | Nebraska | 37 | at | Purdue (8-6,6-4) | 43 | |||
| 10/29/2022 | Illinois (8-5,5-4) | 26 | at | Nebraska | 9 | |||
| 11/5/2022 | Minnesota (9-4,5-4) | 20 | at | Nebraska | 13 | |||
| 11/12/2022 | Nebraska | 3 | at | Michigan (13-1,10-0) | 34 | |||
| 11/19/2022 | Wisconsin (7-6,4-5) | 15 | at | Nebraska | 14 | |||
| 11/25/2022 | Nebraska | 24 | at | Iowa (8-5,5-4) | 17 |
| vs Nebraska | vs Other Opponents | Nebraska compared to OOs | |
| Record: | 8-4 | 73-69 | |
| Points Scored: | 27.58 | 26.27 | -1.31 |
| Points Allowed: | 22.58 | 23.86 | -1.28 |
| Margin: | 5.00 | 2.41 | -2.59 |
| Total Points: | 50.16 | 50.13 | 0.03 |