| 9/4/2021 | Davidson (8-3) | 24 | at | VMI | 45 | Pio | ||
| 9/11/2021 | VMI | 10 | at | Kent State (7-7) | 60 | at MAC | ||
| 9/18/2021 | VMI | 31 | at | Cornell (2-8) | 21 | at Ivy | ||
| 9/25/2021 | Wofford (1-10,0-8) | 23 | at | VMI | 31 | |||
| 10/2/2021 | VMI | 24 | at | The Citadel (4-7,3-5) | 35 | |||
| 10/9/2021 | Chattanooga (6-5,5-3) | 34 | at | VMI | 37 | OT | ||
| 10/16/2021 | VMI | 45 | at | Mercer (7-3,6-2) | 7 | |||
| 10/30/2021 | Samford (4-7,3-5) | 45 | at | VMI | 46 | |||
| 11/6/2021 | VMI | 20 | at | East Tennessee St (11-2,7-1) | 27 | |||
| 11/13/2021 | VMI | 31 | at | Furman (6-5,4-4) | 37 | |||
| 11/20/2021 | Western Carolina (4-7,4-4) | 52 | at | VMI | 24 |
| vs VMI | vs Other Opponents | VMI compared to OOs | |
| Record: | 5-6 | 55-58 | |
| Points Scored: | 33.18 | 28.93 | -4.25 |
| Points Allowed: | 31.27 | 30.00 | 1.27 |
| Margin: | 1.91 | -1.07 | -2.98 |
| Total Points: | 64.45 | 58.93 | 5.52 |