| 9/4/2021 | Davidson | 24 | at | VMI (6-5) | 45 | at SoCon | ||
| 9/11/2021 | Shaw (6-4) | 26 | at | Davidson | 28 | CIAA (D2) | ||
| 9/25/2021 | San Diego (7-4,7-1) | 16 | at | Davidson | 28 | |||
| 10/2/2021 | Davidson | 35 | at | Stetson (3-7,1-6) | 28 | |||
| 10/16/2021 | Presbyterian (2-9,0-8) | 35 | at | Davidson | 70 | |||
| 10/23/2021 | Davidson | 49 | at | Butler (3-8,1-7) | 35 | |||
| 10/30/2021 | Davidson | 29 | at | Morehead State (7-4,6-2) | 22 | |||
| 11/6/2021 | St Thomas (7-3,6-2) | 15 | at | Davidson | 42 | |||
| 11/13/2021 | Davidson | 29 | at | Dayton (6-4,5-3) | 38 | |||
| 11/20/2021 | Drake (2-8,1-6) | 14 | at | Davidson | 45 | |||
| 11/27/2021 | Davidson | 21 | at | Kennesaw St (11-2) | 48 | at BigS |
| vs Davidson | vs Other Opponents | Davidson compared to OOs | |
| Record: | 3-8 | 57-50 | |
| Points Scored: | 29.27 | 27.73 | -1.54 |
| Points Allowed: | 36.36 | 27.96 | 8.40 |
| Margin: | -7.09 | -0.23 | 6.86 |
| Total Points: | 65.63 | 55.69 | 9.94 |