| 9/18/2021 | VMI (6-5) | 31 | at | Cornell | 21 | SoCon | ||
| 9/25/2021 | Cornell | 17 | at | Yale (5-5,4-3) | 23 | |||
| 10/2/2021 | Cornell | 10 | at | Bucknell (1-10) | 21 | at Pat | ||
| 10/9/2021 | Cornell | 10 | at | Harvard (8-2,5-2) | 24 | |||
| 10/15/2021 | Colgate (5-6) | 20 | at | Cornell | 34 | Pat | ||
| 10/23/2021 | Brown (2-8,1-6) | 49 | at | Cornell | 45 | |||
| 10/29/2021 | Princeton (9-1,6-1) | 34 | at | Cornell | 16 | |||
| 11/6/2021 | Cornell | 15 | at | Pennsylvania (3-7,1-6) | 12 | |||
| 11/13/2021 | Cornell | 7 | at | Dartmouth (9-1,6-1) | 41 | |||
| 11/20/2021 | Columbia (7-3,4-3) | 34 | at | Cornell | 26 |
| vs Cornell | vs Other Opponents | Cornell compared to OOs | |
| Record: | 8-2 | 47-46 | |
| Points Scored: | 28.90 | 25.43 | -3.47 |
| Points Allowed: | 20.10 | 26.33 | -6.23 |
| Margin: | 8.80 | -0.90 | -9.70 |
| Total Points: | 49.00 | 51.76 | -2.76 |