| 9/2/2021 | UC Davis | 19 | at | Tulsa (7-6) | 17 | at AAC | ||
| 9/11/2021 | UC Davis | 53 | at | San Diego (7-4) | 7 | at Pio | ||
| 9/18/2021 | Dixie State (1-10) | 27 | at | UC Davis | 60 | WAC | ||
| 9/25/2021 | UC Davis | 17 | at | Weber State (6-5,5-3) | 14 | |||
| 10/2/2021 | Idaho (4-7,3-5) | 20 | at | UC Davis | 27 | |||
| 10/9/2021 | UC Davis | 17 | at | Idaho State (1-10,1-7) | 27 | |||
| 10/16/2021 | Northern Colorado (3-8,2-6) | 3 | at | UC Davis | 32 | |||
| 10/23/2021 | UC Davis | 24 | at | Cal Poly (2-9,1-7) | 13 | |||
| 11/6/2021 | UC Davis | 40 | at | Northern Arizona (5-6,4-4) | 24 | |||
| 11/13/2021 | Eastern Washington (10-3,6-3) | 38 | at | UC Davis | 20 | |||
| 11/20/2021 | Sacramento State (9-3,8-0) | 27 | at | UC Davis | 7 | |||
| 11/27/2021 | UC Davis | 24 | at | South Dakota State (11-4) | 56 | at MVC |
| vs UC Davis | vs Other Opponents | UC Davis compared to OOs | |
| Record: | 4-8 | 62-67 | |
| Points Scored: | 22.75 | 26.59 | 3.84 |
| Points Allowed: | 28.33 | 28.16 | 0.17 |
| Margin: | -5.58 | -1.57 | 4.01 |
| Total Points: | 51.08 | 54.75 | -3.67 |