| 9/2/2021 | Weber State | 17 | at | Utah (10-4) | 40 | at P12 | ||
| 9/11/2021 | Weber State | 41 | at | Dixie State (1-10) | 3 | at WAC | ||
| 9/18/2021 | James Madison (12-2) | 37 | at | Weber State | 24 | CAAF | ||
| 9/25/2021 | UC Davis (8-4,5-3) | 17 | at | Weber State | 14 | |||
| 10/2/2021 | Weber State | 38 | at | Cal Poly (2-9,1-7) | 7 | |||
| 10/15/2021 | Montana State (12-3,7-1) | 13 | at | Weber State | 7 | |||
| 10/23/2021 | Weber State | 35 | at | Eastern Washington (10-3,6-3) | 34 | |||
| 10/30/2021 | Weber State | 40 | at | Idaho State (1-10,1-7) | 17 | |||
| 11/6/2021 | Portland State (5-6,4-4) | 30 | at | Weber State | 18 | |||
| 11/13/2021 | Weber State | 62 | at | Southern Utah (1-10,0-8) | 0 | |||
| 11/20/2021 | Northern Colorado (3-8,2-6) | 17 | at | Weber State | 48 |
| vs Weber State | vs Other Opponents | Weber State compared to OOs | |
| Record: | 5-6 | 60-63 | |
| Points Scored: | 19.55 | 27.53 | 7.98 |
| Points Allowed: | 31.27 | 27.46 | 3.81 |
| Margin: | -11.72 | 0.07 | 11.79 |
| Total Points: | 50.82 | 54.99 | -4.17 |