| 9/4/2021 | North Dakota (5-6) | 35 | at | Idaho State | 14 | MVC | ||
| 9/11/2021 | Idaho State | 10 | at | Nevada (8-5) | 49 | at MW | ||
| 9/25/2021 | Sacramento State (9-3,8-0) | 23 | at | Idaho State | 21 | |||
| 10/2/2021 | Idaho State | 17 | at | Northern Arizona (5-6,4-4) | 48 | |||
| 10/9/2021 | UC Davis (8-4,5-3) | 17 | at | Idaho State | 27 | |||
| 10/16/2021 | Idaho State | 10 | at | Portland State (5-6,4-4) | 31 | |||
| 10/23/2021 | Idaho State | 9 | at | Montana State (12-3,7-1) | 27 | |||
| 10/30/2021 | Weber State (6-5,5-3) | 40 | at | Idaho State | 17 | |||
| 11/6/2021 | Idaho State | 14 | at | BYU (10-3) | 59 | at Ind | ||
| 11/13/2021 | Idaho State | 29 | at | Cal Poly (2-9,1-7) | 32 | |||
| 11/20/2021 | Idaho (4-7,3-5) | 14 | at | Idaho State | 0 |
| vs Idaho State | vs Other Opponents | Idaho State compared to OOs | |
| Record: | 10-1 | 64-56 | |
| Points Scored: | 34.09 | 27.40 | -6.69 |
| Points Allowed: | 15.27 | 25.82 | -10.55 |
| Margin: | 18.82 | 1.58 | -17.24 |
| Total Points: | 49.36 | 53.22 | -3.86 |