| 9/18/2021 | Rhode Island (7-4) | 45 | at | Brown | 24 | CAAF | ||
| 9/24/2021 | Brown | 17 | at | Harvard (8-2,5-2) | 49 | |||
| 10/2/2021 | Brown | 29 | at | Bryant (7-4) | 36 | at NE | ||
| 10/9/2021 | Colgate (5-6) | 10 | at | Brown | 31 | Pat | ||
| 10/16/2021 | Princeton (9-1,6-1) | 56 | at | Brown | 42 | |||
| 10/23/2021 | Brown | 49 | at | Cornell (2-8,1-6) | 45 | |||
| 10/30/2021 | Brown | 17 | at | Pennsylvania (3-7,1-6) | 45 | |||
| 11/6/2021 | Yale (5-5,4-3) | 63 | at | Brown | 38 | |||
| 11/13/2021 | Brown | 17 | at | Columbia (7-3,4-3) | 23 | |||
| 11/20/2021 | Dartmouth (9-1,6-1) | 52 | at | Brown | 31 |
| vs Brown | vs Other Opponents | Brown compared to OOs | |
| Record: | 8-2 | 54-39 | |
| Points Scored: | 42.40 | 24.68 | -17.72 |
| Points Allowed: | 29.50 | 21.14 | 8.36 |
| Margin: | 12.90 | 3.54 | -9.36 |
| Total Points: | 71.90 | 45.82 | 26.08 |