| 9/4/2021 | Bucknell | 0 | at | Sacred Heart (8-4) | 21 | at NE | ||
| 9/11/2021 | Bucknell | 3 | at | Villanova (10-3) | 55 | at CAAF | ||
| 9/18/2021 | Pennsylvania (3-7) | 30 | at | Bucknell | 6 | Ivy | ||
| 10/2/2021 | Cornell (2-8) | 10 | at | Bucknell | 21 | Ivy | ||
| 10/9/2021 | Bucknell | 0 | at | Lafayette (3-8,2-4) | 27 | |||
| 10/16/2021 | Bucknell | 21 | at | Fordham (6-5,4-2) | 66 | |||
| 10/23/2021 | Georgetown (2-8,1-5) | 29 | at | Bucknell | 21 | |||
| 10/30/2021 | Bucknell | 10 | at | Colgate (5-6,5-1) | 33 | |||
| 11/6/2021 | Lehigh (3-8,3-3) | 38 | at | Bucknell | 6 | |||
| 11/13/2021 | Bucknell | 10 | at | Army (9-4) | 63 | at Ind | ||
| 11/20/2021 | Holy Cross (10-3,6-0) | 45 | at | Bucknell | 6 |
| vs Bucknell | vs Other Opponents | Bucknell compared to OOs | |
| Record: | 10-1 | 51-63 | |
| Points Scored: | 37.91 | 22.12 | -15.79 |
| Points Allowed: | 9.45 | 24.58 | -15.13 |
| Margin: | 28.46 | -2.46 | -30.92 |
| Total Points: | 47.36 | 46.70 | 0.66 |