| 9/3/2016 | San Jose State (4-8) | 10 | at | Tulsa | 45 | MW | ||
| 9/10/2016 | Tulsa | 3 | at | Ohio State (11-2) | 48 | at B10 | ||
| 9/17/2016 | North Carolina A&T (9-3) | 21 | at | Tulsa | 58 | MEAC (1AA) | ||
| 9/24/2016 | Tulsa | 48 | at | Fresno State (1-11) | 41 | OT | at MW | |
| 10/7/2016 | SMU (5-7,3-5) | 40 | at | Tulsa | 43 | OT | ||
| 10/15/2016 | Tulsa | 31 | at | Houston (9-4,5-3) | 38 | |||
| 10/22/2016 | Tulane (4-8,1-7) | 27 | at | Tulsa | 50 | |||
| 10/29/2016 | Tulsa | 59 | at | Memphis (8-5,5-3) | 30 | |||
| 11/5/2016 | East Carolina (3-9,1-7) | 24 | at | Tulsa | 45 | |||
| 11/12/2016 | Tulsa | 40 | at | Navy (9-5,7-2) | 42 | |||
| 11/19/2016 | Tulsa | 35 | at | UCF (6-7,4-4) | 20 | |||
| 11/25/2016 | Cincinnati (4-8,1-7) | 37 | at | Tulsa | 40 | |||
| 12/19/2016 | Central Michigan (6-7) | 10 | vs | Tulsa | 55 | Miami Beach Bowl | MAC |
| vs Tulsa | vs Other Opponents | Tulsa compared to OOs | |
| Record: | 3-10 | 76-74 | |
| Points Scored: | 29.85 | 29.64 | -0.21 |
| Points Allowed: | 42.46 | 27.09 | 15.37 |
| Margin: | -12.61 | 2.55 | 15.16 |
| Total Points: | 72.31 | 56.73 | 15.58 |