| 9/1/2016 | Tennessee-Martin (7-5) | 7 | at | Cincinnati | 28 | OVC (1AA) | ||
| 9/10/2016 | Cincinnati | 38 | at | Purdue (3-9) | 20 | at B10 | ||
| 9/15/2016 | Houston (9-4,5-3) | 40 | at | Cincinnati | 16 | |||
| 9/24/2016 | Miami-Ohio (6-7) | 20 | at | Cincinnati | 27 | MAC | ||
| 10/1/2016 | South Florida (11-2,7-1) | 45 | at | Cincinnati | 20 | |||
| 10/8/2016 | Cincinnati | 9 | at | Connecticut (3-9,1-7) | 20 | |||
| 10/22/2016 | East Carolina (3-9,1-7) | 19 | at | Cincinnati | 31 | |||
| 10/29/2016 | Cincinnati | 13 | at | Temple (10-4,8-1) | 34 | |||
| 11/5/2016 | BYU (9-4) | 20 | at | Cincinnati | 3 | Ind | ||
| 11/12/2016 | Cincinnati | 3 | at | UCF (6-7,4-4) | 24 | |||
| 11/18/2016 | Memphis (8-5,5-3) | 34 | at | Cincinnati | 7 | |||
| 11/25/2016 | Cincinnati | 37 | at | Tulsa (10-3,6-2) | 40 |
| vs Cincinnati | vs Other Opponents | Cincinnati compared to OOs | |
| Record: | 8-4 | 77-64 | |
| Points Scored: | 26.92 | 31.64 | 4.72 |
| Points Allowed: | 19.33 | 27.70 | -8.37 |
| Margin: | 7.59 | 3.94 | -3.65 |
| Total Points: | 46.25 | 59.34 | -13.09 |