| 9/4/2010 | Doane Tigers 7 @ Morningside 40 | † |
| 9/11/2010 | Morningside 23 @ Nebraska Wesleyan Prairie Wolves 12 | † |
| 9/18/2010 | Briar Cliff Chargers 12 @ Morningside 58 | † |
| 9/25/2010 | Morningside 36 @ Midland Lutheran Warriors 7 | † |
| 10/2/2010 | Morningside 20 @ Northwestern IA Red Raiders 17 | † |
| 10/9/2010 | Dordt Defenders 0 @ Morningside 71 | † |
| 10/16/2010 | Morningside 3 @ Sioux Falls Cougars 28 | † |
| 10/23/2010 | Concordia NE Bulldogs 3 @ Morningside 17 | † |
| 10/30/2010 | Hastings Broncos 7 @ Morningside 43 | † |
| 11/13/2010 | Morningside 45 @ Dakota Wesleyan Tigers 8 | † |
| 11/20/2010 | Dickinson State Blue Hawks 17 @ Morningside 38 | |
| 11/27/2010 | Morningside 10 @ MidAmerica Nazarene Pioneers 34 |