| 9/11/2010 | Wooster Scots 17 @ Wabash 21 | † |
| 9/18/2010 | Wabash 45 @ Ohio Wesleyan Battling Bishops 21 | † |
| 9/25/2010 | Chicago Maroons 14 @ Wabash 31 | |
| 10/2/2010 | Wabash 40 @ Kenyon Lords 3 | † |
| 10/9/2010 | Wabash 20 @ Washington U Bears 24 | |
| 10/16/2010 | Oberlin Yeomen 21 @ Wabash 42 | † |
| 10/23/2010 | Wabash 55 @ Denison Big Red 20 | † |
| 10/30/2010 | Allegheny Gators 3 @ Wabash 20 | † |
| 11/6/2010 | Wabash 17 @ Wittenberg Tigers 34 | † |
| 11/13/2010 | DePauw Tigers 0 @ Wabash 47 |