| 9/4/2010 | Susquehanna Crusaders 6 @ Moravian 12 | † |
| 9/11/2010 | Moravian 10 @ McDaniel Green Terror 13 | † |
| 9/18/2010 | Moravian 6 @ Lebanon Valley Flying Dutchmen 21 | |
| 9/25/2010 | Johns Hopkins Blue Jays 41 @ Moravian 3 | † |
| 10/2/2010 | Moravian 24 @ Dickinson Red Devils 16 | † |
| 10/9/2010 | Moravian 21 @ Gettysburg Bullets 33 | † |
| 10/16/2010 | Franklin & Marshall Diplomats 17 @ Moravian 24 | † |
| 10/23/2010 | Moravian 42 @ Juniata Eagles 0 | † |
| 10/30/2010 | Ursinus Bears 17 @ Moravian 24 | † |
| 11/13/2010 | Muhlenberg Mules 13 @ Moravian 14 | † |
| 11/20/2010 | Moravian 26 @ Wilkes Colonels 14 (ECAC Southeast Bowl Championship) |