| 9/4/2010 | Chowan Braves 14 @ The Citadel 56 | |
| 9/11/2010 | The Citadel 6 @ Arizona Wildcats 52 | |
| 9/18/2010 | Presbyterian Blue Hose 14 @ The Citadel 26 | |
| 9/25/2010 | The Citadel 14 @ Furman Paladins 31 | † |
| 10/2/2010 | Western Carolina Catamounts 24 @ The Citadel 13 | † |
| 10/9/2010 | Chattanooga Moccasins 28 @ The Citadel 10 | † |
| 10/16/2010 | The Citadel 10 @ Appalachian State Mountaineers 39 | † |
| 10/23/2010 | Georgia Southern Eagles 20 @ The Citadel 0 | † |
| 10/30/2010 | The Citadel 0 @ Wofford Terriers 35 | † |
| 11/6/2010 | Elon Phoenix 27 @ The Citadel 16 | † |
| 11/20/2010 | The Citadel 13 @ Samford Bulldogs 12 | † |