| 9/3/2022 | Hardin-Simmons (9-2) | 79 | at | Wayland Baptist | 14 | ASWC (D3) | ||
| 9/10/2022 | Lyon (1-9,0-9) | 14 | at | Wayland Baptist | 37 | |||
| 9/17/2022 | Wayland Baptist | 24 | at | Langston (6-4,5-4) | 56 | |||
| 9/24/2022 | Texas College (1-9,1-8) | 31 | at | Wayland Baptist | 65 | |||
| 10/1/2022 | Texas Wesleyan (8-2,7-2) | 59 | at | Wayland Baptist | 16 | |||
| 10/8/2022 | Wayland Baptist | 10 | at | Panhandle State (4-6,4-5) | 38 | |||
| 10/15/2022 | Wayland Baptist | 17 | at | Louisiana College (7-4,6-3) | 37 | |||
| 10/29/2022 | Southwestern Assemblies of God (7-4,6-3) | 30 | at | Wayland Baptist | 0 | |||
| 11/5/2022 | Wayland Baptist | 14 | at | Ottawa AZ (7-2,7-2) | 38 | |||
| 11/12/2022 | Arizona Christian (8-3,7-2) | 41 | at | Wayland Baptist | 14 |
| vs Wayland Baptist | vs Other Opponents | Wayland Baptist compared to OOs | |
| Record: | 8-2 | 50-43 | |
| Points Scored: | 42.30 | 30.59 | -11.71 |
| Points Allowed: | 21.10 | 27.00 | -5.90 |
| Margin: | 21.20 | 3.59 | -17.61 |
| Total Points: | 63.40 | 57.59 | 5.81 |