| 8/25/2022 | Dakota Wesleyan | 19 | at | Dakota State (6-4) | 29 | at NSAA | ||
| 9/3/2022 | Dakota Wesleyan | 30 | at | Jamestown (4-7,3-7) | 34 | |||
| 9/10/2022 | Dakota Wesleyan | 7 | at | Northwestern IA (13-1,9-1) | 54 | |||
| 9/17/2022 | Dordt (7-3,7-3) | 38 | at | Dakota Wesleyan | 7 | |||
| 9/24/2022 | Dakota Wesleyan | 13 | at | Hastings (7-4,6-4) | 32 | |||
| 10/1/2022 | Concordia NE (4-6,4-6) | 20 | at | Dakota Wesleyan | 12 | |||
| 10/8/2022 | Dakota Wesleyan | 13 | at | Doane (4-6,4-6) | 16 | |||
| 10/15/2022 | Briar Cliff (1-10,1-9) | 24 | at | Dakota Wesleyan | 31 | |||
| 10/22/2022 | Midland U. (8-3,7-3) | 22 | at | Dakota Wesleyan | 13 | |||
| 10/29/2022 | Dakota Wesleyan | 14 | at | Morningside (11-1,10-0) | 70 | |||
| 11/5/2022 | Mount Marty (3-8,2-8) | 34 | at | Dakota Wesleyan | 38 |
| vs Dakota Wesleyan | vs Other Opponents | Dakota Wesleyan compared to OOs | |
| Record: | 9-2 | 59-51 | |
| Points Scored: | 33.91 | 26.74 | -7.17 |
| Points Allowed: | 17.91 | 24.87 | -6.96 |
| Margin: | 16.00 | 1.87 | -14.13 |
| Total Points: | 51.82 | 51.61 | 0.21 |