| 8/27/2022 | Waldorf (7-4) | 42 | at | Briar Cliff | 24 | NSAA | ||
| 9/3/2022 | Dordt (7-3,7-3) | 35 | at | Briar Cliff | 13 | |||
| 9/10/2022 | Jamestown (4-7,3-7) | 25 | at | Briar Cliff | 31 | |||
| 9/17/2022 | Briar Cliff | 23 | at | Morningside (11-1,10-0) | 59 | |||
| 9/24/2022 | Mount Marty (3-8,2-8) | 41 | at | Briar Cliff | 19 | |||
| 10/1/2022 | Briar Cliff | 9 | at | Hastings (7-4,6-4) | 28 | |||
| 10/8/2022 | Midland U. (8-3,7-3) | 56 | at | Briar Cliff | 21 | |||
| 10/15/2022 | Briar Cliff | 24 | at | Dakota Wesleyan (2-9,2-8) | 31 | |||
| 10/29/2022 | Briar Cliff | 7 | at | Northwestern IA (13-1,9-1) | 56 | |||
| 11/5/2022 | Concordia NE (4-6,4-6) | 45 | at | Briar Cliff | 10 | |||
| 11/12/2022 | Briar Cliff | 14 | at | Doane (4-6,4-6) | 28 |
| vs Briar Cliff | vs Other Opponents | Briar Cliff compared to OOs | |
| Record: | 10-1 | 60-51 | |
| Points Scored: | 40.55 | 26.59 | -13.96 |
| Points Allowed: | 17.73 | 24.59 | -6.86 |
| Margin: | 22.82 | 2.00 | -20.82 |
| Total Points: | 58.28 | 51.18 | 7.10 |