| 8/27/2022 | St Mary KS (4-7) | 10 | at | Midland U. | 64 | KCAC | ||
| 9/3/2022 | Hastings (7-4,6-4) | 10 | at | Midland U. | 14 | |||
| 9/10/2022 | Midland U. | 20 | at | Doane (4-6,4-6) | 6 | |||
| 9/17/2022 | Midland U. | 20 | at | Mount Marty (3-8,2-8) | 7 | |||
| 9/24/2022 | Jamestown (4-7,3-7) | 10 | at | Midland U. | 21 | |||
| 10/1/2022 | Morningside (11-1,10-0) | 47 | at | Midland U. | 12 | |||
| 10/8/2022 | Midland U. | 56 | at | Briar Cliff (1-10,1-9) | 21 | |||
| 10/22/2022 | Midland U. | 22 | at | Dakota Wesleyan (2-9,2-8) | 13 | |||
| 10/29/2022 | Concordia NE (4-6,4-6) | 31 | at | Midland U. | 41 | |||
| 11/5/2022 | Midland U. | 10 | at | Northwestern IA (13-1,9-1) | 42 | |||
| 11/12/2022 | Dordt (7-3,7-3) | 17 | at | Midland U. | 8 |
| vs Midland U. | vs Other Opponents | Midland U. compared to OOs | |
| Record: | 3-8 | 57-54 | |
| Points Scored: | 19.45 | 27.50 | 8.05 |
| Points Allowed: | 26.18 | 26.38 | -0.20 |
| Margin: | -6.73 | 1.12 | 7.85 |
| Total Points: | 45.63 | 53.88 | -8.25 |