| 9/3/2022 | Shenandoah | 27 | at | Methodist (5-5) | 10 | at USASC | ||
| 9/10/2022 | North Carolina Wesleyan (3-7) | 0 | at | Shenandoah | 45 | USASC | ||
| 9/17/2022 | Shenandoah | 34 | at | Maryville (5-5) | 29 | at USASC | ||
| 10/1/2022 | Ferrum (1-9,1-6) | 0 | at | Shenandoah | 20 | |||
| 10/8/2022 | Shenandoah | 17 | at | Bridgewater VA (9-1,6-1) | 23 | |||
| 10/15/2022 | Guilford (2-8,1-6) | 35 | at | Shenandoah | 38 | |||
| 10/22/2022 | Randolph-Macon (11-1,7-0) | 35 | at | Shenandoah | 21 | |||
| 10/29/2022 | Shenandoah | 45 | at | Averett (3-7,1-6) | 0 | |||
| 11/5/2022 | Hampden-Sydney (5-5,4-3) | 7 | at | Shenandoah | 23 | |||
| 11/12/2022 | Shenandoah | 16 | at | Washington and Lee (5-5,3-4) | 14 | 3OT |
| vs Shenandoah | vs Other Opponents | Shenandoah compared to OOs | |
| Record: | 2-8 | 47-45 | |
| Points Scored: | 15.30 | 28.22 | 12.92 |
| Points Allowed: | 28.60 | 25.97 | 2.63 |
| Margin: | -13.30 | 2.25 | 15.55 |
| Total Points: | 43.90 | 54.19 | -10.29 |