| 9/3/2022 | Rose-Hulman | 14 | at | DePauw (9-2) | 17 | at NCA | ||
| 9/10/2022 | Trine (7-3) | 24 | at | Rose-Hulman | 23 | MIAA | ||
| 9/17/2022 | Albion (9-1) | 49 | at | Rose-Hulman | 17 | MIAA | ||
| 10/1/2022 | Rose-Hulman | 45 | at | Anderson (1-9,1-6) | 7 | |||
| 10/8/2022 | Manchester (1-9,0-7) | 14 | at | Rose-Hulman | 48 | |||
| 10/15/2022 | Rose-Hulman | 48 | at | Bluffton (2-8,2-5) | 20 | |||
| 10/22/2022 | Franklin (4-6,4-3) | 0 | at | Rose-Hulman | 49 | |||
| 10/29/2022 | Defiance (3-7,3-4) | 35 | at | Rose-Hulman | 76 | |||
| 11/5/2022 | Rose-Hulman | 47 | at | Hanover (5-5,5-2) | 17 | |||
| 11/12/2022 | Rose-Hulman | 31 | at | Mt St Joseph (10-1,7-0) | 40 |
| vs Rose-Hulman | vs Other Opponents | Rose-Hulman compared to OOs | |
| Record: | 4-6 | 47-45 | |
| Points Scored: | 22.30 | 29.18 | 6.88 |
| Points Allowed: | 39.80 | 28.64 | 11.16 |
| Margin: | -17.50 | 0.54 | 18.04 |
| Total Points: | 62.10 | 57.82 | 4.28 |